Results 81 to 90 of about 1,424,908 (288)

Improving Turnaround Times for Routine Antimicrobial Sensitivity Testing Following European Committee on Antimicrobial Susceptibility Testing Methodology in Patients with Bacteraemia

Antibiotics
Background/Objectives: Bacteraemia can be fatal without antibiotic intervention. Antibiotic Susceptibility Testing (AST) provides the necessary information for targeted antibiotic therapy; however, the traditional method using disc diffusion can take ...
Raewyn Edmondson, Kordo Saeed, Steve Green, Matthew O’Dwyer   +3 more
doaj   +1 more source

Computational investigation of sulphate diffusion into the dog disc

2011 18th Iranian Conference of Biomedical Engineering (ICBME), 2011
We proposed a model to investigate the transient diffusion of drug (sulphate) into the intervertebral disc. Using finite element method, drug diffusion was simulated and the concentration of diffused drug in each region of disc including Nucleus pulpous (NP), Inner annulus fibroses (IA), and Outer annulus fibroses (OA) was measured.
Motaghinasab, S, Shirazi-Adl, A, Urban, J, Parnianpour, M, Hoviattalab, M   +4 more
openaire   +2 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Effective diffusion tensor computed by homogenization [PDF]

, 2013
The convergence of the long-time apparent diffusion tensor of diffusion magnetic resonance imaging (dMRI) to the effective diffusion tensor obtained by mathematical homogenization theory was considered for two-compartment geometric models containing non ...
Grebenkov, Denis, Poupon, Cyril, Li, Jing-Rebecca Li, Bihan, Denis Le, Nguyen, Dang Van   +4 more
core   +1 more source

disc-re/Contrail-Statistics: Contrail Statistics Tool

, 2022
This analysis tool evaluates the atmospheric contrail formation conditions based on ECMWF ERA-5 Reanalysis data and helps to obtain an overview of the frequency of contrail formation over the last 10 years at different altitudes, seasons and ...
disc-re
core   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Electroacupuncture attenuates intervertebral disc degeneration by upregulating aquaporins via the cAMP/PKA pathway

Journal of Orthopaedic Surgery and Research
Background Intervertebral disc degeneration (IVDD) is characterized by a decrease in extracellular matrix (ECM) and water loss, which is a major cause of low back pain (LBP). Electroacupuncture (EA) has long been used to relieve LBP in IVDD.
Min Wang, Jia-Bao Huang, Jing Zou, Guo-fu Huang   +3 more
doaj   +1 more source

Effects of oxidation and hot corrosion in a nickel disc alloy [PDF]

, 2008
This paper describes work to study oxidation and hot corrosion damage in nickel disc alloy RR1000. Oxidation damage has been characterised via mass change data from thermogravimetric analyses at temperatures from 700 to 800 ºC and cyclic oxidation ...
Encinas-Oropesa, Adriana, J.R. Nicholls, N.J. Simms, Hardy, M. C., A.J. Leggett, A. Encinas-Oropesa, M.C. Hardy, Leggett, A. J., Nicholls, John R., G.L. Drew, Drew, G. L., Simms, Nigel J.   +11 more
core   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source