Results 101 to 110 of about 77,204 (294)

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

Role of DTI in cases of cervical spondylosis presented with compression myelopathy: Could it explain the clinical radiological mismatch?!

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine, 2018
Introduction and aim of work: The work aimed to assess if Diffusion Tensor Imaging and Fiber Tractography (DTI) can explain the contradiction between the side of brachialgia in patients with cervical spondylosis and the side of cord compression by the ...
Heba Ibrahim Ali Ibrahim, Alaa Saleh
doaj   +1 more source

Relative contribution of biological variation and technical variables to zone diameter variations of disc diffusion susceptibility testing [PDF]

open access: yes, 2016
OBJECTIVES Disc diffusion is still largely based on manual procedures. Technical variations originate from inoculum preparation, variations in materials, individual operator plate streaking and reading accuracy.
Böttger, Erik C   +5 more
core   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

Fosfomycin—Overcoming Problematic In Vitro Susceptibility Testing and Tricky Result Interpretation: Comparison of Three Fosfomycin Susceptibility Testing Methods

open access: yesAntibiotics
Background: Fosfomycin (FOS) is an older antimicrobial agent newly rediscovered as a possible treatment for infections with limited therapeutic options (e.g., Gram-negative bacteria with difficult-to-treat resistance, DTR), especially in intravenous form.
Jan Závora   +3 more
doaj   +1 more source

ANTIMICROBIAL STUDY OF FLOWERING PLANTS

open access: yesJournal of Academia, 2021
Antimicrobials are a common term that refers to a group of drugs that can kill microorganism which antibiotic, antifungal and antivirus. Antimicrobial acts to inhibit the growth of microorganisms.
Siti Khadijah Abdul Karim , Yasmin Said
doaj  

Tigecycline and intravenous fosfomycin zone breakpoints equivalent to the EUCAST MIC criteria for Enterobacteriaceae

open access: yesJournal of Infection in Developing Countries, 2012
Introduction: Tigecycline and intravenous (i.v.) fosfomycin could be alternative therapeutic options for the treatment of carbapenemase-possessing Enterobacteriaceae bacterial infections.
Fernando Pasteran   +7 more
doaj   +1 more source

Assessment of degradation of proteoglycans and matrix proteins in intervertebral disc degeneration by diffusion weighted MRS

open access: yes, 2013
This study investigated the capability of diffusion weighted magnetic resonance spectroscopy (DW-MRS) for assessing the changes in carbohydrates region (3.5-4.2ppm) during intervertebral disc degeneration (IVDD).
Wang, AM, Cao, P, Yang, J, Wu, EX
core  

Relative contribution of biological variation and technical variables to zone diameter variations of disc diffusion susceptibility testing [PDF]

open access: yes, 2021
Objectives Disc diffusion is still largely based on manual procedures. Technical variations originate from inoculum preparation, variations in materials, individual operator plate streaking and reading accuracy.
Furrer, Reinhard   +5 more
core  

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