Results 111 to 120 of about 1,974,786 (294)

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Assessment and analysis of polymyxin sensitivity using the disc elution method on clinical isolates resistant to carbapenems

International Journal of Applied and Experimental Biology
Elevated mortality rates have drawn the focus of researchers to multidrug-resistant Gram-negative Enterobacteriaceae over the last decade. In the case of multidrug-resistant Gram-negative bacteria, particularly carbapenem-resistant Enterobacteriaceae ...
Muhammad Raheel Awan, Maimoona Sabir, Hussan ibne Shoukani, Nimra Nasir, Sadia Khalil, Misbah Asif, Faisal Zaman   +6 more
doaj  

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

The trend of antibiotic resistance of Staphylococcus aureus isolated in clinical specimens in a referral hospital Shahid mohammadi hospital at Bandar abbas, South of Iran (2009-2014) [PDF]

Disease and Diagnosis, 2017
Background: Staphylococcus is an important pathogen for humans, which is found on skin, mucous membranes and oropharynx of healthy individuals. The bacteria can cause a range of infections from simple wounds and skin abscesses to severe infections such ...
Tahereh Khalafi, Seyede Rooya Mohebbi, Fatemeh Moradi, Fatemeh Khanipour, Ramin Mahmoudian, Maryam Montaseri, Tasnim eqhbal eftekhaari, Afsaneh Karmostaji, Maryam ansari   +8 more
doaj  

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Role of DTI in cases of cervical spondylosis presented with compression myelopathy: Could it explain the clinical radiological mismatch?!

The Egyptian Journal of Radiology and Nuclear Medicine, 2018
Introduction and aim of work: The work aimed to assess if Diffusion Tensor Imaging and Fiber Tractography (DTI) can explain the contradiction between the side of brachialgia in patients with cervical spondylosis and the side of cord compression by the ...
Heba Ibrahim Ali Ibrahim, Alaa Saleh
doaj   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

The Correlation Of The Diffusion Values In Lumbar Intervertebral Discs With Disc Degeneration And Age

Ankara Üniversitesi Tıp Fakültesi Mecmuas, 2008
Purpose: To evaluate the correlation of the diffusion values in lumbar intervertebral discs with disc degeneration and age.Materials and Methods: Diffusion-weighted imaging of the lumbar spine was performed in fifty patients. ADC values were recorded for each disc. All discs were visually as being normal or as showing at least one of two MR findings of
Cisel Yazgan, Simay Kara, Çetin Evliyaoğlu   +2 more
openaire   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source