Results 41 to 50 of about 39,086 (289)

Utilization of CT scanning associated with complex spine surgery. [PDF]

, 2017
BackgroundDue to the risk associated with exposure to ionizing radiation, there is an urgent need to identify areas of CT scanning overutilization. While increased use of diagnostic spinal imaging has been documented, no previous research has estimated ...
Andersson, Gunnar BJ, Block, Jon E, Garfin, Steven R, Patel, Vikas V, Resnick, Donald L   +4 more
core   +1 more source

Inhibition of Hypersialylation in Human Intervertebral Disc Degeneration Modulates Inflammation and Metabolism

Advanced Science, EarlyView.
Glycosylation, specifically hypersialylation, is identified as a critical factor in human intervertebral disc (IVD) degeneration—a major cause of low back pain. This study demonstrates that inhibiting sialylation reduces inflammation and oxidative stress in IVD tissues, suggesting new therapeutic possibilities.
Kieran Joyce, Aert F. Scheper, Aung Myat Phyo, Roisin O’ Flaherty, Richard Drake, Aiden Devitt, Martina Marchetti‐Deschmann, Radka Saldova, Abhay Pandit   +8 more
wiley   +1 more source

Degenerative Spine Surgery: Our Experience

Nepal Journal of Neuroscience, 2017
Degenerative disease is the commonest spinal problem that any neurosurgeon or spinal surgeon encounters in his/her daily practice. Many such cases can be managed conservatively with appropriate investigations, while many others may need surgical ...
Prabin Shrestha , Anish M Singh , Isha Dhungana   +2 more
doaj   +1 more source

Laparoscopic Assisted Fusion of the Lumbosacral Spine: A Biomechanical and Histologic Analysis of the Open Versus Laparoscopic Technique in an Animal Model [PDF]

, 1997
Study Design. An animal model for laparoscopic lumbosacral fusion. Objectives. To compare the biomechanical and histologic results of open to laparoscopic lumbosacral discectomy and fusion in an animal model. Background Data.
Cahn, Nguyen, Eck, Jason C., Lim, Tae Hong, McGrady, Linda M., Riley, Lee H., III, Toth, Jeffrey M., Yoshida, Hiryuki   +6 more
core   +1 more source

TRAIL, DR5 and Caspase 3-dependent Apoptosis in Vessels of Diseased Human Temporomandibular Joint Disc. An Immunohistochemical Study [PDF]

, 2010
To evaluate the apoptosis involvement in the angiogenesis as a self-limiting process in patients with temporomandibular joint (TMJ) degenerated disc vessels, we assessed, by immunohistochemistry, the detection of TRAIL, its death receptor DR5 and caspase
Almeida, Luis Eduardo, Caltabiano, M., Leonardi, Rosalia, Loreto, Carla, Migliore, M. R.   +4 more
core   +4 more sources

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Dysphagia Characteristics in High Versus Low Vagal Unilateral Vocal Fold Paralysis

The Laryngoscope, EarlyView.
High vagal etiology of unilateral vocal fold paralysis (UVFP) is linked to greater swallowing dysfunction compared to low vagal etiology of UVFP, with higher rates of premature spillage, pharyngeal residue, penetration and aspiration on instrumental swallow assessment; and higher prevalence of diet and behavioral modifications recommended.
Madeline Miles Marker, Liam W. Gallagher, Aanish Puri, Jesse Hoffmeister, Scott Lunos, Heather Erickson, Gina Cruciani, Joslyn Kahn, Stephanie Misono, Raluca Gray   +9 more
wiley   +1 more source

Sequential Changes of Plasma C-Reactive Protein, Erythrocyte Sedimentation Rate and White Blood Cell Count in Spine Surgery : Comparison between Lumbar Open Discectomy and Posterior Lumbar Interbody Fusion. [PDF]

, 2014
ObjectiveC-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are often utilized to evaluate for postoperative infection. Abnormal values may be detected after surgery even in case of non-infection because of muscle injury, transfusion ...
Ament, Jared D, Choi, Man Kyu, Kim, Kee D, Kim, Sung Bum   +3 more
core  

Chiropractic spinal manipulative therapy versus physical therapist‐led exercise and the risk of cauda equina syndrome in adults with lumbar disc herniation, stenosis, or radiculopathy

PM&R, EarlyView.
Abstract Background Cauda equina syndrome is a surgical emergency often caused by lumbar disc herniation. Spinal manipulative therapy is commonly used for lumbar spine disorders, but case reports have raised concerns it may precipitate cauda equina syndrome. One cohort study suggested no increased risk, although it did not focus on patients with lumbar
Robert J. Trager, Anthony N. Baumann, Romeo‐Paolo T. Perfecto, Christine M. Goertz   +3 more
wiley   +1 more source

Efficacy of different approaches of spinal endoscopy in the treatment of L 4-5 intervertebral disc herniation

Zhongguo linchuang yanjiu
Objective To compare the clinical efficacy of two approaches under spinal endoscopy in the treatment of L 4-5 intervertebral disc herniation. Methods A retrospective analysis was performed for 148 patients with L 4-5 intervertebral disc herniation ...
ZHU Hai, XU Yongyi, SUN Xuan, JI Feng
doaj   +1 more source