Results 81 to 90 of about 39,086 (289)

Propionibacterium acnes evades microbicidal phagocytosis by inhibiting the mitochondrial biogenesis of nucleus pulposus cells

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 295-317, January 2026.
P. acnes infection impairs the mitochondrial biogenesis of nucleus pulposus cells (NPCs) through the AMPK/SIRT‐1/PGC‐1α signaling pathway. This results in impaired mitochondria that are unable to generate sufficient ATP, and impaired delivery of mitochondrial reactive oxygen species to carry out the bactericidal process effectively.
Lemeng Ren   +9 more
wiley   +1 more source

Patients' Experiences of Day Surgery: A Qualitative Systematic Review

open access: yesJournal of Advanced Nursing, Volume 82, Issue 1, Page 247-271, January 2026.
ABSTRACT Aim To examine how patients experience day surgery. Design Systematic review using Thomas and Harden's framework for synthesis and analysed through Ricoeur's theory of interpretation. Methods and Data Sources Systematic searches in MEDLINE, CINAHL and EMBASE (September 2023) identified qualitative studies focusing on patients' lived ...
Josephine Ransborg Sig   +4 more
wiley   +1 more source

Tapentadol extended release for the management of chronic neck pain [PDF]

open access: yes, 2017
BACKGROUND: The role of opioids in the management of chronic neck pain is still poorly investigated. No data are available on tapentadol extended release (ER).
Coluzzi, Flaminia
core   +1 more source

LUMBAR DISCECTOMY

open access: yesThe Professional Medical Journal, 2011
Background: Discectomy is the standard treatment for lumber disc disease. Fenestration operations involved lot of tissue dissection and so the complications. Instead the endoscopic discectomy involved less tissue dissection but limited exposure.
M.SHAHID SMAIJA   +2 more
openaire   +2 more sources

Quantitative MRI Signal Changes of the Spinal Cord as Predictors of Suboptimal Surgical Outcomes in Degenerative Cervical Myelopathy

open access: yesOrthopaedic Surgery, Volume 18, Issue 1, Page 84-92, January 2026.
Ninety‐four patients diagnosed with increased signal intensity (ISI) on T2‐weighted MRI and treated with anterior cervical decompression for DCM between January 2021 and June 2023 were reviewed, Higher signal change ratio (SCR), the presence of snake‐eye appearance (SEA), and long symptoms predict poor DCM outcomes, highlighting the need for early ...
Xingsheng Zhang   +5 more
wiley   +1 more source

Quality of systematic reviews: an example of studies comparing artificial disc replacement with fusion in the cervical spine. [PDF]

open access: yes, 2015
Cervical artificial disc replacement (C-ADR) is now an alternative to anterior cervical discectomy and fusion (ACDF). Many studies have evaluated the efficacy of C-ADR compared with ACDF.
Anderson PA   +20 more
core   +3 more sources

The Implementation of Persistent Spinal Pain Syndrome (PSPS): Mechanism‐Based Recommendations

open access: yesPain Practice, Volume 26, Issue 1, January 2026.
ABSTRACT Background In 2021, the term persistent spinal pain syndrome (PSPS) was introduced. PSPS type 2 (PSPS‐T2) replaced the unsatisfactory term failed back surgery syndrome (FBSS). PSPS type 1 (PSPS‐T1) is a clinical picture of signs and symptoms of FBSS but without prior surgery. PSPS applies to any spinal level.
Simon Thomson   +7 more
wiley   +1 more source

Small Bowel Transection as a Rare Complication of Lumbar Disc Surgery: Report of a Case.

open access: yesArchives of Clinical and Experimental Surgery, 2015
Small bowel injury resulting from the perforation of anterior longitudinal ligament during lumbar disc surgery is very rare, with prompt diagnosis being difficult.
Zafer Kilbas   +4 more
doaj   +1 more source

Nondestructive, fatigue cyclic, and ramped cyclic biomechanical testing of surgical techniques for stabilization of the lumbosacral junction in dogs

open access: yesVeterinary Surgery, Volume 55, Issue 1, Page 176-186, January 2026.
Abstract Objective To compare transarticular screw fixation (TSF), pedicle screw‐rod fixation (PSRF), and screws and polymethylmethacrylate (SPMMA) for stabilization of the canine lumbosacral junction (LSJ). Study design Ex vivo biomechanical study.
Lucas A. Smolders   +4 more
wiley   +1 more source

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