Results 81 to 90 of about 3,984,951 (355)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Modeling of Process for Level Changes in Cascade of Two Channel Water Reservoirs in Case of Flooding
Наука и техника, 2019 For the last decades in the Republic of Belarus, there is a tendency of decreasing river flow, but at the same time the probability of flood is increasing.
V. V. Veremenyuk +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Climate change and river discharge: case study Kolubara River, Beli brod hydrological gauge [PDF]
Glasnik Srpskog Geografskog Društva, 2012 This paper analyzes climate change and its impact on river discharge. This issue is very well studied worldwide, but in Serbia so far has been poorly studied.
Burić Dragan +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Lightning discharge identification system [PDF]
, 1981 A system for differentiating between cloud to cloud and cloud to ground lightning discharges is described which includes an electric field antenna that senses the rate of charge of an electric field produced by a lightning discharge.
Lennon, C. L.
core +1 more source
Quality and Cost Analysis of Nurse Staffing, Discharge Preparation, and Postdischarge Utilization [PDF]
, 2011 Objectives. To determine the impact of unit-level nurse staffing on quality of discharge teaching, patient perception of discharge readiness, and postdischarge readmission and emergency department (ED) visits, and cost-benefit of adjustments to unit ...
Bobay, Kathleen +2 more
core +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Ultraviolet hydrogen-discharge lamp [PDF]
, 1975 Device provides stable flux output for calibration of ultraviolet ...
Kerr, D. E.
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source