Results 51 to 60 of about 3,162,083 (256)
Analysis of discharge rates in rectangular slit, ogee, and sharp-crested weirs
Frontiers in Built EnvironmentClimate change has made flash floods increasingly common. It's crucial to have confidence in the structural integrity of dams during a flash flood. According to the International Commission on Large Dams (ICOLD), approximately one-third of dam failures ...
Hossein Sohrabzadeh Anzani +3 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Empirical investigation on the discharge capacity of an emergency ship lock
Shuili Shuiyun Gongcheng XuebaoThe emergency ship lock, an integral hydraulic structure within the Changshanjiang hub series, serves crucial roles in flood discharge, lock maintenance, and specialized shipping operations. Despite its significance, both domestically and internationally,
LIN Yanping +3 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Experimental study on discharge capacity of street inlet in urban flooding
Shui kexue jinzhan, 2020 Urban flood disasters have occurred frequently in recent years in China, causing a serious threat to urban management and the safety of people and property.
Qian CHEN, Junqiang XIA, Boliang DONG
doaj +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
International Journal of Electrochemical Science, 2018 PbO2 thin film is essential for applications in lead acid batteries system. In this work, PbO2 thin films with different surface microstructure were fabricated through electrodeposition technique by controlling the deposition current density. Though PbO2
Xuan Zhao +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
International Journal of Electrochemical Science, 2018 Disordered spinel LiNi0.5Mn1.5O4 (LNMO) was successfully synthesised via a molten-salt method using a mixture of LiOH⋅H2O and LiNO3 salts. The precursor was annealed at 750, 850 or 950 °C for 12 h, and the effects of calcination temperature on the ...
Nabilah Mokhtar +2 more
doaj +1 more source