Results 41 to 50 of about 3,162,083 (256)

Missouri Work Zone Capacity: Results of Field Data Analysis, TPF-5(081), 2011 [PDF]

, 2011
This report presents the results of work zone field data analyzed on interstate highways in Missouri to determine the mean breakdown and queue-discharge flow rates as measures of capacity.

core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Investigating the Electrochemical Characteristics of Lithium Vanadium Phosphate Cathode Synthesized by the Solution Combustion Method Utilizing Cetyltrimethylammonium Bromide as a Fuel for Lithium-Ion Batteries Applications [PDF]

Journal of Advanced Materials in Engineering
Introduction and Objectives: Optimization of vanadium phosphate compounds through the control of synthesis methods plays a key role in enhancing their performance. In this research, the effect of adding cetyltrimethylammonium bromide with different molar
Mohammad Tahernejad Javazm, Masoud Hasheminiasari, Seyed Morteza Masoudpanah   +2 more
doaj   +1 more source

Bankfull discharge and recurrence intervals in Irish rivers [PDF]

, 2012
Different definitions of the bankfull condition in rivers are based on morphological characteristics, boundary conditions and geometrical properties.
Ahilan, Sangaralingam, O'Sullivan, J. J., O\u27Sullivan, J. J., Brauders, N, Ahilan, S, Healy, Darren, Healy, D, Bruen, M, Brauders, Neill, O'Sullivan, JJ, Bruen, Michael   +10 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Discharge communication in the emergency department : on quantity- and content-definition and on the benefit of information structuring [PDF]

, 2015
Health and diseases have always accompanied humans and are important topics to talk about. Appropriate communication, however, can only have an impact on one’s health if the essential content is transferred and if the message is sent in a way enabling ...
Ackermann, Selina
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Modeling discharge capacity of labyrinth weirs through a learning machine approach [PDF]

Journal of Applied Research in Water and Wastewater, 2019
In this paper, the discharge coefficient of weirs is simulated by the extreme learning machine (ELM). To this end, seven different ELM models are introduced by the input parameters.
Mohammadali Izadbakhsh, Reza Hajiabadi
doaj   +1 more source

Predicting death and readmission after intensive care discharge [PDF]

, 2008
Background: Despite initial recovery from critical illness, many patients deteriorate after discharge from the intensive care unit (ICU). We examined prospectively collected data in an attempt to identify patients at risk of readmission or death after ...
B.H. Cuthbertson, J.A. Cook, A.J. Campbell, Cook, Jonathan Alistair, Adey, Gillian, Campbell, Alison J., Cuthbertson, Brian, G. Adey   +7 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source