Results 41 to 50 of about 196,537 (265)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Synthesis, characterization and electrochemical performance of core/shell structured carbon coated silicon powders for lithium ion battery negative electrodes

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2017
Surface of nano silicon powders were coated with amorphous carbon by pyrolysis of polyacronitrile (PAN) polymer. Microstructural characterization of amorphous carbon coated silicon powders (Si-C) were carried out using scanning electron microscopy (SEM)
Tuğrul Çetinkaya
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Extremely Pure Mg2FeH6 as a Negative Electrode for Lithium Batteries

Energies, 2018
Nanocrystalline samples of Mg-Fe-H were synthesized by mixing of MgH2 and Fe in a 2:1 molar ratio by hand grinding (MIX) or by reactive ball milling (RBM) in a high-pressure vial.
Sergio Brutti, Luca Farina, Francesco Trequattrini, Oriele Palumbo, Priscilla Reale, Laura Silvestri, Stefania Panero, Annalisa Paolone   +7 more
doaj   +1 more source

II. On stratified discharges. V. Discharge from a condenser of large capacity [PDF]

Proceedings of the Royal Society of London, 1878
Abstract The principal object of the following communication is to describe an instrumental arrangement which has proved very convenient for the production of steady striæ. The first attempt which was made nearly two years ago (February, 1876), consisted in charging a Leyden battery of nine large jars by means of an induction coil ...
openaire   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Experimental Study of Discharge Coefficient of Symmetric and Asymmetric Rectangular Labyrinth Weirs

علوم آب و خاک, 2022
The discharge coefficient of labyrinth weirs increases with increasing the crest length in a certain width range. The present research was carried out in a laboratory flume with a length of 8 m, a width of 0.6 m, and a height of 0.6 m.
H. Elahifar, O. Tayari, N. Yazdanpanah, M. momeni   +3 more
doaj  

Discharge Capacity of Prefabricated Vertical Drain Confined in-clay

Geosynthetics Engineering Journal, 2000
This paper reports the long-term discharge capacities of four types of prefabricated vertical drains (PVDs) confined in clay. The results indicate that under clay confinement, the PVD discharge capacities significantly reduced with time. The discharge capacity reduction may be caused by creep deformation of the PVD filter or clogging of the drainage ...
Miura, N., Chai, J. C.
openaire   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source