Results 51 to 60 of about 232,000 (307)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Research on Calculation Method for Discharge Capacity of Draining Well in Tailing Ponds Based on “Simplification-Fitting” Method

open access: yesEnergies, 2022
The existing empirical formulas concerning draining systems are complex in their expression: there are difficulties in locating the intersection point among different flow patterns and parameters vary depending on the water level, resulting in a large ...
Sha Wang   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Battery Lifetime Prediction via Neural Networks with Discharge Capacity and State of Health

open access: yesEnergies, 2022
The market share of electric vehicles (EVs) has grown exponentially in recent years to reduce air pollution and greenhouse gas emissions. The principal part of an EV is the energy storage system, which is usually the batteries.
Jamila Hemdani   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Improving the Discharge Capacity of the Al Butera River

open access: yesIOP Conference Series: Earth and Environmental Science, 2023
AbstractIn the province of Maysan, the Al Butera River is one of the most significant tributaries of the Tigris River. It has a length of 48.8 km and reaches the Central Marshes in the south of Maysan from downstream of Al Butera Regulator. Villages and farmland suffer significant.
Hashim M Alhamdi, Hayder A Al Thamiry
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Electrochemical Properties of Nb-Substituted Zr-Ti-Ni Hydrogen Storage Alloy Negative Electrodes for Nickel-Metal Hydride Batteries

open access: yesMetals, 2018
Crystal structure, pressure-composition isotherms and electrochemical properties of the Zr0.6−xTi0.4NbxNi (x = 0.01, 0.02, and 0.05) alloys were investigated. Their X-ray diffraction profiles demonstrated that all the Zr0.6−xTi0.4NbxNi alloys
Akihiro Matsuyama   +3 more
doaj   +1 more source

Discharge Capacity of Prefabricated Vertical Drain Confined in-clay

open access: yesGeosynthetics Engineering Journal, 2000
This paper reports the long-term discharge capacities of four types of prefabricated vertical drains (PVDs) confined in clay. The results indicate that under clay confinement, the PVD discharge capacities significantly reduced with time. The discharge capacity reduction may be caused by creep deformation of the PVD filter or clogging of the drainage ...
Miura, N., Chai, J. C.
openaire   +2 more sources

Approach Flow Depth Influence on Nonlinear Weir Discharge Capacity

open access: yes, 2021
The high hydraulic efficiency and the compactness of nonlinear weirs favor their use in several rehabilitation or new dams projects. Main types of nonlinear weirs are labyrinth and piano key weirs.The purpose of this paper is to provide indications on ...
Pirotton, Michel   +2 more
core   +2 more sources

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