Results 21 to 30 of about 61,320 (256)

The Study of Triangular Flow Regulators

Applied Sciences
The paper presents the results of tests of flow regulators with a triangular prismatic cross-section chamber. The aim of the paper was to experimentally and numerically (CFD) assess the water flow for different design variants of the regulators.
Marek Ochowiak, Magdalena Olszewska, Daniel Janecki, Sylwia Włodarczak, Andżelika Krupińska, Magdalena Matuszak   +5 more
doaj   +1 more source

Investigation of Discharge Coefficients for Single Element Lean Direct Injection Modules

Energies, 2018
Lean direct injection (LDI) combustion has a high potential as a low pollution combustion method for gas turbines. The present research aims to further investigate the discharge coefficient of an LDI module, axial swirler and convergent outlet under non ...
Han Yu, Pengfei Zhu, Jianqin Suo, Longxi Zheng   +3 more
doaj   +1 more source

Simulation of Main Plasma Parameters of a Cylindrical Asymmetric Capacitively Coupled Plasma Micro-Thruster using Computational Fluid Dynamics

Frontiers in Physics, 2015
Computational fluid dynamics (CFD) simulations of a radio-frequency (13.56 MHz) electro-thermal capacitively coupled plasma (CCP) micro-thruster have been performed using the commercial CFD-ACE+ package.
Amelia eGreig, Christine eCharles, Roderick William Boswell   +2 more
doaj   +1 more source

Modification of Roughness Coefficients of Water Distribution Network Using Optimization Method [PDF]

رویکردهای نوین در مهندسی عمران, 2018
Due to the breadth and complexity of water distribution networks, modeling of these networks is essential for proper utilization and proper network management. Determination of network coefficients is the more importance in network modeling.
Hamid Azarvash, Mehdi Dini
doaj   +1 more source

Secretory Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized for Vaso‐Occlusive Pain Episodes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman, Maria Yasmine, Dunia Hatabah, Noor Alzraikat, Frank Harris, Lou Ann Brown, Satheesh Chonat, Nitya Bakshi, Chris A. Rees, Carlton Dampier, Claudia R. Morris   +10 more
wiley   +1 more source

Numerical Study of Discharge Coefficients for Side-Damaged Compartments

Journal of Marine Science and Engineering
Accurately evaluating the buoyancy and stability of damaged ships, particularly the flow rate of the water inflow through damaged openings, is of great significance for ship rescue and emergency repair.
Siwen Tian, Fei Peng, Zhanzhi Wang, Jingda Li   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source