Results 31 to 40 of about 617,959 (301)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Development of an Industrial Partial Discharge Calibrator and Its Performance Tests
IEEE AccessIn industrial electromechanical manufacturing, ensuring the accuracy of electrical partial discharge measurements is crucial for the reliability and efficiency of electrical power systems.
Ismail Karaman, Ali Ajder, Ismail Nakir
doaj +1 more source
Calibration Proposal for UHF Partial Discharge Measurements at Power Transformers
Energies, 2019 The continuous, non-intermitted service of electrical grids relies on the reliability of their assets, e.g., power transformers. Local insulation defects can result in serve failures such as breakdowns with severe subsequent costs. The prevention of such
Martin Siegel +10 more
doaj +1 more source
Using modelled discharge to develop satellite-based river gauging: a case study for the Amazon Basin [PDF]
Hydrology and Earth System Sciences, 2018 River discharge measurements have proven invaluable to monitor the global water cycle, assess flood risk, and guide water resource management. However, there is a delay, and ongoing decline, in the availability of gauging data and stations are highly ...
J. Hou +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Siting Considerations for Satellite Observation of River Discharge
Water Resources ResearchWith growing global capability for satellite measurement of river discharge (flow) comes a need to understand and reduce error in satellite‐based discharge measurements. Satellite‐based discharge estimates are based on measurements of water surface width,
Jack Eggleston +5 more
doaj +1 more source
Estimating River Discharge With Swath Altimetry: A Proof of Concept Using AirSWOT Observations
Geophysical Research Letters, 2019 The forthcoming Surface Water and Ocean Topography (SWOT) satellite mission will provide global measurements of the free surface of large rivers, providing new opportunities for remote sensing‐derived estimates of river discharge in gaged and ungaged ...
S. Tuozzolo +10 more
doaj +1 more source
Characterization of Ground Water Discharge to Hampton Harbor [PDF]
, 2003 The project goals were to assess inter-tidal groundwater discharge and concurrent nutrient loading to Hampton Harbor. This will include maps of suspected groundwater discharge zones and measurements of nutrient loading.
Ballestero, Thomas
core +2 more sources
Negative ions formed in N2/CH4/Ar discharge – a simulation of Titan's atmosphere chemistry [PDF]
, 2009 The formation of negative ions produced in a negative point-to-plane corona discharge fed by a Ar/N2//CH4/ gas mixture has been studied using mass spectrometry.
Bakes +15 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source