Results 61 to 70 of about 617,959 (301)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Modeling the Effects of the Cathode Composition of a Lithium Iron Phosphate Battery on the Discharge Behavior

open access: yesEnergies, 2013
This paper reports a modeling methodology to predict the effects on the discharge behavior of the cathode composition of a lithium iron phosphate (LFP) battery cell comprising a LFP cathode, a lithium metal anode, and an organic electrolyte.
Won Il Cho   +4 more
doaj   +1 more source

Effect of length of the observed dataset on the calibration of a distributed hydrological model [PDF]

open access: yesProceedings of the International Association of Hydrological Sciences, 2015
Calibration of hydrological models in ungauged basins is now a hot research topic in the field of hydrology. In addition to the traditional method of parameter regionalization, using discontinuous flow observations to calibrate hydrological models has ...
X. Cui, W. Sun, J. Teng, H. Song, X. Yao
doaj   +1 more source

Preliminary validation of an indirect method for discharge evaluation of Pertuso Spring (Central Italy) [PDF]

open access: yes, 2016
This paper deals with the results of the first year of the Environmental Monitoring Plan, related to the catchment project of Pertuso Spring, which is going to be exploited to supply an important water network in the South part of Roma district.
De Filippi, F. M.   +2 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A First Look at River Discharge Estimation From SWOT Satellite Observations

open access: yesGeophysical Research Letters
The Surface Water and Ocean Topography (SWOT) satellite has the potential to transform global hydrologic science by offering simultaneous and synoptic estimates of river discharge and other hydraulic variables.
Konstantinos M. Andreadis   +41 more
doaj   +1 more source

FIELD TESTING OF THE SMBF FLUME

open access: yesJournal of Agricultural Engineering, 2007
At first, in this paper the stage-discharge relationship of a new flume, originally proposed by Samani and Magallanez, for measuring flow discharge in open channels is reviewed.
Costanza Di Stefano   +2 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Developing Formulae for combined weir and orifice (case study: EL-Fayoum weirs)

open access: yesAlexandria Engineering Journal, 2013
In this study, Formulae were developed for rehabilitated weirs (i.e., combined weirs and orifices, weirs with 1 or 2 pipes in their bodies). Several sites of the existing rehabilitated weirs in El-Fayoum were visited. During the visits, measurements were
Ahmed M. El-Belasy
doaj   +1 more source

Boundary-induced effect on the spoke-like activity in ExB plasma

open access: yes, 2019
The spoke instability in an $E\times B$ Penning discharge is shown to be strongly affected by the boundary that is perpendicular to $B$ field lines. The instability is the strongest when bounded by dielectric walls.
Kaganovich, Igor   +5 more
core   +1 more source

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