Results 101 to 110 of about 2,047,533 (295)

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

Advanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li, Hui Yuan, Honglei Xiao, Xiaodong Liu, Wenguo Cui   +4 more
wiley   +1 more source

Data‐Driven Modeling of Composition–Processing–Microstructure Relations for Recycled Aluminum Cast Alloys

Advanced Science, EarlyView.
Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang, Waleed Mohammed, Dierk Raabe   +2 more
wiley   +1 more source

Association of quality of nursing care with violence load, burnout, and listening climate

Israel Journal of Health Policy Research
Background Violence against nurses is common. Previous research has recommended further development of the measurement of violence against nurses and integration of the individual and ward-related factors that contribute to violence against hospital ...
Sigal Shafran Tikva, Gillie Gabay, Or Shkoler, Ilya Kagan   +3 more
doaj   +1 more source

MXenes: Reshaping Cross-Disciplinary Innovation and Application Frontiers in Biomedical Engineering

Engineered Science
MXenes have demonstrated significant advantages in smart diagnostic systems, neural engineering interfaces and tissue regeneration engineering due to their abundant surface functional groups, large specific surface area, metal-like conductivity and ...
Wu Wang, Chuang Gong, Jide Zhang, Yihuan Kan, Shaochen Zhou, Min Tang, Yabing Gan, Jingfeng Wang   +7 more
doaj   +1 more source

Creative Industries Innovation Centre Closure Q&A.pdf

, 2015
Information about the of the Creative Industries Innovation Centre in Q&A form, with information about creative business support services through the Entrepreneurs' Infrastructure Programme, final Biztro sessions, and a link to the Creative Industries ...
Creative Industries Innovation Centre
core  

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Advanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta, Shuyi Wang, Boyan Zhang, Ning Liu, Yingchen Han, Aoran Liu, Ying Xu, Tingsong Chen, Ye Zhang, Qiuhua Luo, Tao Han   +10 more
wiley   +1 more source

Bringing Discipline into Transdisciplinary Communications -The ISO 56000 Family of Innovation Standards- [PDF]

Journal of Systemics, Cybernetics and Informatics
Trans-disciplinary communication generates new knowledge that may lead to inventions that may be processed into innovations by ambidextrous organizations operating in a global innovation ecosystem.
Rick Fernandez, William Swart
doaj  

Reconstruction and Practical Turn of the Core Issue of Self in Psychopathology

Yixue yu zhexue
From the three dimensions of metaphilosophical reflection, phenomenological foundation and integration mechanism construction, this paper explores the marginalization of self-related issues in psychopathology, and systematically verifies the theoretical ...
Ming ZHANG
doaj   +1 more source

Pathological Copper Overload Reprograms SOD1 Activation via COMMD1 to Promote Senescence and Fibrosis

Advanced Science, EarlyView.
This study uncovers a previously unrecognized copper‐COMMD1‐SOD1 regulatory axis, revealing that pathological copper overload paradoxically suppresses SOD1 activity by promoting COMMD1‐dependent disruption of SOD1 homodimerization. These findings redefine the regulatory role of copper in SOD1 biology and provide novel mechanistic insight into the ...
Yuqing Liu, Jing Liu, Wenqian Zhou, Yangyang Niu, Yan Zheng, Yiguo Liu, Yingying Zhang, Chen Yu   +7 more
wiley   +1 more source

Disciplinary Inbreeding or Disciplinary Integration? [PDF]

Journal of Systemics, Cybernetics and Informatics
This article explores the risks of disciplinary inbreeding caused by disciplinary isolations in what has been called disciplinary silos. Disciplinary isolation necessarily reduces the disciplinary intra-variety and, according e the First Law of ...
Nagib Callaos
doaj