Results 161 to 170 of about 36,932 (299)

Artificial Intelligence‐Based Body Composition Analysis Reveals Sex‐Specific Prognostic Markers and Their Clinical Value in Gastric Cancer: A Multicenter Study

open access: yesAdvanced Science, EarlyView.
This study applied AI to quantify multidimensional body composition from CT images in gastric cancer and healthy controls. Distinct sex‐specific patterns and disease‐related alterations were identified and were associated with survival. Higher muscle and fat measures were linked to improved outcomes.
Tianxiang Li   +13 more
wiley   +1 more source

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

open access: yesAdvanced Science, EarlyView.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma   +22 more
wiley   +1 more source

Rebalancing psychology in China. [PDF]

open access: yesCommun Psychol
Tao X, Pu Y, Kong XZ.
europepmc   +1 more source

Anticipatory innovation

open access: yes, 2004
*This article is free to read on the publisher's website*\ud \ud This article examines the role of innovation in society, arguing that a failure of foresight in the practical design and development of innovations has been a significant causal factor in ...
Ramos, Jose M.
core  

Lessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective

open access: yesAdvanced Science, EarlyView.
Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT Cryopreservation is
Dominika Wilczok   +4 more
wiley   +1 more source

HEALTH AND URBAN PLANNING. ATTEMPTS AT DISCIPLINARY INTEGRATION AND INNOVATION

open access: yes, 2018
This paper presents the results of research on the role of urban planning in promoting actions to improve the health/well-being of inhabitants from the perspective of a new alliance between health and urban planning. Based on the WHO’s definition of health and some experiences within the European Healthy Cities movement, the paper focuses on the ...
C. Camaioni   +5 more
openaire   +2 more sources

Workshop report-Vulnerability in multi-hazard risks: Addressing its complexity and dynamics. [PDF]

open access: yesiScience
Santos AP   +14 more
europepmc   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng   +14 more
wiley   +1 more source

Enhancing Education Research Through Cross-Disciplinary Integration: A Systematic Literature Review

open access: yesAraştırma Temelli Etkinlik Dergisi
In an era of increasingly complex educational challenges, effective solutions necessitate multi-disciplinary teamwork. The goal of this systematic literature review (SLR) was to identify strategies for encouraging cross-disciplinary collaborations in ...
David Onen
doaj  

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