Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang +11 more
wiley +1 more source
Establishing a Multidisciplinary Medical Imaging Clinical Educator Team Across a Large Tertiary Health Network: A Workforce Education Model. [PDF]
Lavender I +4 more
europepmc +1 more source
Instantiating the Innovation of Meaning Into the Customer Experience: Lessons From Retail Services
The experiential service innovation is becoming a common competitive arena both for product-oriented (e.g. original brand manufacturers like Apple, Zara, Ikea) and service-oriented (e.g.
F. Artusi, E. Bellini
core
Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li +12 more
wiley +1 more source
Enhancing Education Research Through Cross-Disciplinary Integration: A Systematic Literature Review
In an era of increasingly complex educational challenges, effective solutions necessitate multi-disciplinary teamwork. The goal of this systematic literature review (SLR) was to identify strategies for encouraging cross-disciplinary collaborations in ...
David Onen
doaj
An exploratory pilot study of integrated mini-CEX and DOPS assessments in general medicine residency: feasibility and longitudinal outcomes. [PDF]
Pang S +6 more
europepmc +1 more source
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng +12 more
wiley +1 more source
Supporting open science practices at multidisciplinary scale. [PDF]
Soper D +2 more
europepmc +1 more source
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang +10 more
wiley +1 more source

