Results 131 to 140 of about 37,779 (299)

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Procedure of the administrative court relating to interpleading in disputes about disciplinary action arising from The NACC Disciplinary Breach Indication

การศึกษาค้นคว้าอิสระเรื่อง “กระบวนพิจารณาคดีของศาลปกครองเกี่ยวกับการร้องสอด ในคดีพิพาทเกี่ยวกับการลงโทษทางวินัยซึ่งเกิดจากการชี้มูลความผิดของคณะกรรมการ ป.ป.ช.” มีวัตถุประสงค์ของการศึกษา ดังนี้ 1) เพื่อศึกษาแนวคิดทฤษฎีเกี่ยวกับการดำเนินการทางวินัยข ...
สุพัตรา คำแท่ง
core  

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Metal‐Enhanced Charge Transport and its Mechanism in Atomically Precise Ruthenium Single‐Molecule Devices

Advanced Science, EarlyView.
An atomically precise platform was developed for investigating single‐molecule charge transport. This innovative platform enables the creation of highly uniform molecular devices using ruthenium‐based molecules. It reveals a significant enhancement in molecular conductance due to the metallic ruthenium center and a unique barrier‐lowering effect during
Jie Guo, Qinghua Gao, Ping Duan, Cong Zhao, Huimin Wen, Xiaoyan He, Lucie Norel, Yuzhe Zhang, Chunwen Wang, Wu Zhou, Xinyue Chang, Ju Wang, Stéphane Rigaut, Mingliang Li, Chuancheng Jia, Xuefeng Guo   +15 more
wiley   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

Application of disciplinary responsability in employment and civil servant relationships.

, 2018
Bakalaura darba temats „Disciplināratbildības piemērošana darba tiesiskajās un civildienesta ierēdņu nodarbinātības attiecībās” ir aktuāls, jo Darba likumā, salīdzinot ar Valsts civildienesta ierēdņu disciplināratbildības likumu, disciplināratbildības ...
Štamere, Ilze
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Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Disciplinary action in case of territory manager in Thailand

, 2014
L'action disciplinaire dans la fonction publique territoriale en Thaïlande est intéressante car plusieurs problèmes apparaissent ainsi que de nombreux contentieux administratifs en matière de procédure.
Amonwat, Patpong
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MFPD: A Multiple Fungal Pathogen Detection Pipeline Across Diverse Habitats

Advanced Science, EarlyView.
The MFPD pipeline integrates a comprehensive ITS reference database of fungal pathogens, optimized parameters, and algorithms tailored for both full‐length and subregion sequences that balance accuracy and computational efficiency; it enables high‐throughput, species‐level identification from amplicon sequencing data, supporting large‐scale ...
Yi Shen, Xinrun Yang, Jiabao Yu, Yaozhong Zhang, Tianjie Yang, Yang Gao, Xiaofang Wang, Alexandre Jousset, Waseem Raza, Fang‐Jie Zhao, Qirong Shen, Gaofei Jiang, Zhong Wei, Yangchun Xu   +13 more
wiley   +1 more source

Hydrogen (H2) Recovery From Hydrogen Sulfide (H2S): Current Technologies, Challenges, and Future Outlook

Advanced Science, EarlyView.
ABSTRACT Hydrogen sulfide (H2S) can be transformed into hydrogen (H2) through several chemical and catalytic processes, offering a promising route for both waste treatment and clean H2 production. This colorless, flammable, and toxic gas is found abundantly in swamps, volcanoes, hot springs, sewages, other natural gas fields, and even in refineries and
Divyesh Cirikonda, Astrid Campos‐Mata, Sehmus Ozden, Shreyasi Chattopadhyay, Pulickel M. Ajayan   +4 more
wiley   +1 more source