Results 211 to 220 of about 37,779 (299)

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

Hepatic Myelopathy as a Rare but Reversible Neurological Complication Post Transjugular Intrahepatic Portosystemic Shunt (TIPS) Insertion in Liver Cirrhosis. [PDF]

Eur J Case Rep Intern Med
Zhu A, Clements W, Wesselingh R, Janko N.   +3 more
europepmc   +1 more source

CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning

Advanced Science, EarlyView.
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang, Zexi Chen, Yuanxiang Miao, Zuolin Shen, Deyu Cai, Shijie Tang, Yun Xue, Weifeng Guo, Hongbin Ji, Jian Liu, Kazuyuki Aihara, Luonan Chen   +11 more
wiley   +1 more source

Reporting verbs across genre sets and research paradigms: a corpus-based analysis of denotation and evaluation in applied linguistics research articles. [PDF]

Front Psychol
Deng L, Li X.
europepmc   +1 more source

Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

The impact of multidisciplinary team on surgical procedure and complications in duodenal tumor patients. [PDF]

BMC Cancer
Jiang Z, Wu K, Liu K, Zhang Y, Cao Y, Deng S, Gu J, Qin L, Mao F, Wang J, Xue Y, Chen M, Cheng D, Zou F, Huang N, Dai J, Wang H, Cai W, Tao K, Wang J, Liao X, Cai K.   +21 more
europepmc   +1 more source

Synergistic Effect of Gradient Conductivity and Gradient Microstructures Enabled Ultrasensitive and Ultrabroad Linear Flexible Tactile Sensors

Advanced Science, EarlyView.
A design of double gradient effect is proposed to resolve the contradictory optimization on sensitivity and linearity of piezoresistive tactile sensors. The ultrawide linearity is realized by the sequential trigger of pressure‐induced gradient conductivity‐enabled linear current owing to the gradient microstructures.
Yao Fang, Yiwei Wang, Bing Zheng, Liu Yang, Jingyi Yue, Qian Zhou, Jinrong Huang, Yongyun Mao, Qian Li, Jifei Wang, Dongsheng Tang, Yuxin Tang, Bingpu Zhou, Bing Ji   +13 more
wiley   +1 more source

Visual function and cerebrospinal fluid volume along the optic nerve in patients with spontaneous cerebrospinal fluid rhinorrhea: a cross-sectional study. [PDF]

BMC Ophthalmol
Zhang Z, Lei K, Xia J, Yang Z, Liu P, Xue H.   +5 more
europepmc   +1 more source

Causal‐Guided Ultra‐Long‐Term Time Series Forecasting Via Anticipated Covariates

Advanced Science, EarlyView.
Often treated as unknown, information from the future remains underutilized.We demonstrate that in a coupled dynamical system, providing the future state of the effect enables accurate forecasting of the cause for a long timesteps. A time series forecasting paradigm that introduces anticipated covariates to represent such known future states is ...
Jintong Zhao, Yufei Liu, Ruixi Huang, Zhongxue Gan, Siyang Leng   +4 more
wiley   +1 more source

Regulation and criminal law enforcement in healthcare: an uneasy alliance or partners in crime? [PDF]

BMC Health Serv Res
Amelink Q, Weenink JW, Leistikow I.
europepmc   +1 more source