Results 151 to 160 of about 4,465,671 (320)

The Interrelation Between Military Discipline Infraction and Military Criminal Charge in Indonesia

open access: yesNurani Hukum
Violations of the Military Discipline Law that culminate in a disciplinary tribunal’s decision possess only minimal binding force. In other words, the tribunal’s ruling merely serves as a recommendation to the superior vested with punitive authority ...
Regita Wienda Amalia   +1 more
doaj   +1 more source

Physics‐Guided Descriptors Enable Data‐Efficient Prediction of Battery Coulombic Efficiency

open access: yesAdvanced Science, EarlyView.
This work integrates multiscale simulations with data‐driven approaches to predict Coulombic efficiency (CE). Multiscale simulations of battery systems are performed to extract Physics‐Guided descriptors and construct a dataset. Machine learning models trained on this dataset are then subjected to interpretable analysis to identify the most influential
Qintao Sun   +9 more
wiley   +1 more source

Charting the Future of Stereoselective Carbohydrate Synthesis: The Essential Role of Cross‐Disciplinary Innovation

open access: yesAdvanced Science, EarlyView.
Cross‐disciplinary endeavors are blossoming across the broad chemical sciences. This perspective provides a glimpse into the rewarding interdisciplinary journey taken by the Charles Loh research group in pioneering the σ‐hole based catalytic glycosylation strategy.
Charles C. J. Loh
wiley   +1 more source

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu   +10 more
wiley   +1 more source

Serving as a medical expert witness: Avoiding common errors and potential pitfalls

open access: yesAnnals, Academy of Medicine, Singapore
The medical expert witness plays a crucial role in providing objective, informed opinions that can influence the outcome of court trials and disciplinary proceedings.
Sin Yew Wong
doaj   +1 more source

(Fe4N/GaN)@GC: A Bifunctional Electrocatalyst for High‐Performance Rechargeable Zinc‐Air Batteries

open access: yesAdvanced Science, EarlyView.
This work demonstrates that an unprecedented Fe4N/GaN heterostructure, stabilized by a graphitized carbon shell, induces interfacial charge redistribution and optimizes oxygen‐intermediate adsorption, enabling highly efficient bifunctional ORR/OER electrocatalysis for rechargeable zinc‐air batteries.
Xin‐Yuan Wei   +8 more
wiley   +1 more source

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

open access: yesAdvanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu   +15 more
wiley   +1 more source

Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants

open access: yesAdvanced Science, EarlyView.
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr   +6 more
wiley   +1 more source

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

open access: yesAdvanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu   +12 more
wiley   +1 more source

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

open access: yesAdvanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su   +5 more
wiley   +1 more source

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