Results 171 to 180 of about 4,465,671 (320)

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

Advanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou, Ruihua Ji, Qinglu Zang, Mingkang Wang, Lingling Zhou, Yingliang Wei, Di Yang, Yue Wu, Hongxu Zhu, Jianrong Wu, Xiaojun Cai, Wenxian Du, Junjie Cheng, An Zeng, Yuehua Li   +14 more
wiley   +1 more source

From complaints to ethical-professional education: a study based on nursing ethical disciplinary proceedings. [PDF]

Rev Bras Enferm
Serpa R, Schneider DG, Pires DEP, Benedet SA, Amadigi FR.   +4 more
europepmc   +1 more source

ADMISSIBILITY AND EVIDENTIARY VALUE OF THE RESULTS OF COVERT INVESTIGATIVE (SEARCH) ACTIONS AND OPERATIONAL-SEARCH ACTIVITY MATERIALS IN DISCIPLINARY PROCEEDINGS AGAINST JUDGES, PROSECUTORS, AND ATTORNEYS: THE DOCTRINE OF PROCEDURAL INTEGRITY AND A COMPARATIVE LEGAL ANALYSIS

Juridical scientific and electronic journal
M. Pohoretskyi
semanticscholar   +1 more source

Disciplinary Proceedings in the Matters of Public (State) Servants - Applicability of Article 6 of the ECHR?

, 2016
The submitted article analyzes whether disciplinary proceedings in the affairs of civil (state) servants fall under Art. 6 of the European Convention on Human Rights, which would guarantee a right to a fair trial at the international (European) level. In 
Chadima, Marek
core  

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

Advanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun, Hengjie Xu, Sheng Yang, Jiahui Zhou, Chuanxin Tian, Hongxu Nie, Chi Jin, Tuo Wang, Zhihao Chen, Junwei Tang, Yifei Feng, Xiaowei Wang, Yueming Sun   +12 more
wiley   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source

Bioethics and Medical Litigation in France: An Exploratory Study. [PDF]

J Eval Clin Pract
Nader R, Stoeklé HC, Shehba LS, Jazat P, Hervé C.   +4 more
europepmc   +1 more source

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

Advanced Science, EarlyView.
A mitochondria‐derived tRNA half, mt‐5’‐tiRNA‐Tyr, is upregulated in colorectal cancer tissues and plasma and promotes tumor proliferation. It binds HARS2 and promotes CPT1A‐associated HARS2 K91 succinylation, disrupts HARS2–mt‐tRNA‐His association, impairs mitochondrial translation, enhances succinate‐linked metabolic reprogramming, and shows promise ...
Xinliang Gu, Danping Zhu, Xinwei Liu, Shangshang Hu, Xincheng Yang, Junjie Nie, Tao Xu, Yuqin Pan, Mu Xu, Huiling Sun, Shukui Wang   +10 more
wiley   +1 more source

Contours of the transatlantic regulatory landscape: A research agenda towards the reform of US state pharmacy board disciplinary functions. [PDF]

Explor Res Clin Soc Pharm
Johnson D, Umaru N, Gallagher CT.
europepmc   +1 more source

Regulatory support of disciplinary proceedings in Ukraine

Вісник Харківського національного університету внутрішніх справ, 2018
Досліджено нормативно-правового забезпечення дисциплінарного провадження в Україні залежно від виду дисциплінарної відповідальності. Проаналізовано поняття «дисциплінарне провадження», «трудова дисципліна», «службова дисципліна», «дисциплінарний проступок», «простий та грубий дисциплінарні проступки», які відрізняються залежно від нормативно-правового ...
openaire   +1 more source