Results 121 to 130 of about 1,210,291 (287)

Situated responsibility in interdisciplinary research ethics: Comparative perspectives from Moldova, Japan and France

Research Ethics Review
This paper designs and explores the concept of situated ethical responsibility (SER) within interdisciplinary research ethics, drawing on comparative perspectives from Moldova, Japan, and France.
Sanda Caracentev, Dorina Rosca
doaj   +1 more source

"Negotiorum Gestio" in Family Medicine, Informed Consent Obtainment, and Disciplinary Responsibility. [PDF]

Int J Family Med, 2016
Birkeland S.
europepmc   +1 more source

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

Advanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu, Qing Li, Yiyang Xu, Zitao Wang, Hua Shu, Yangfan Wu, Fang Lu, Zhimin Huang, Bo Zhang, Hongwei Liang, Changying Xing, Huijuan Mao, Yanggang Yuan   +12 more
wiley   +1 more source

Disciplinary responsibility in the National Armed Forces.

, 2012
Autora izvēlētā bakalaura darba tēma – „Disciplināratbildība Nacionālajos broņotajos spēkos”, kuras aktualitātes pamatā ir ne tikai militārpersonu īpašais statuss un atbildība, bet arī masu saziņas līdzekļos paustais, ka bruņotajos spēkos ir notikuši ...
Rusiņš, Viktors
core  

A Personalized Haplotype‐Resolved Near‐Gapless Genome Framework for Somatic Variant Discovery in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A patient‐specific, haplotype‐resolved genome framework improves detection and interpretation of somatic variants in hepatocellular carcinoma. Using multi‐platform sequencing, the personalized assembly resolves complex regions including centromeres and MHC/HLA loci, enhances structural variant discovery, and links regulatory alterations to allele ...
Jiazheng Lin, Yao Xiao, Shuangzi Luo, Yifan Li, Wenfei Zhang, Xiaoyu Zhang, Xinyi Wang, Di Wu, Jieru Hong, Yongkun Luan, Xun Huang, Yixiu Wang, Ningbo Wu, Xiaoxiao Hu, Fei Zhao, Wei Li, Xiao Luo, Bi Shi   +17 more
wiley   +1 more source

Multifaceted perception of school climate: association between students’ and teachers’ perceptions and other teacher factors

Frontiers in Education
IntroductionThis study aimed to investigate whether there is a significant association between teachers’ and students’ perceptions of school climate, and if not, whether teacher factors are associated with the respective perceptions.MethodsThe ...
Ikue Hirata, Ikue Hirata, Tomoko Nishimura, Tomoko Nishimura, Tomoko Nishimura, Yuko Osuka, Yuko Osuka, Manabu Wakuta, Manabu Wakuta, Nobuaki Tsukui, Nobuaki Tsukui, Nobuaki Tsukui, Kenji J. Tsuchiya, Kenji J. Tsuchiya, Atsushi Senju, Atsushi Senju   +15 more
doaj   +1 more source

A Single‐Amino‐Acid Ligand for LAT1: A Minimalist and Modular Platform for Lysosome‐Targeted Degradation of Membrane Proteins

Advanced Science, EarlyView.
LA‐LYTAC repurposes the cancer‐enriched amino acid transporter LAT1 as a lysosomal trafficking receptor for targeted membrane‐protein degradation. A single phenylalanine‐derived ligand, modularly linked to antibodies or small‐molecule binders, recruits PD‐L1, EGFR, or integrins to LAT1, triggering transporter‐mediated internalization, lysosomal ...
Liquan Zhu, Ke Liu, Haotian Liu, Chaoqi He, Xiaozhen Liu, Xin Zeng, Misha Mao, Yuxiao Mu, Ying Li, Qinghui Zheng, Hongchao Tang, Da Qian, Xuli Meng   +12 more
wiley   +1 more source

"Disciplinary responsibility of employees and civil servants audits problems"

, 2014
Bakalaura darba tēma ir ”Darbinieku un civildienesta ierēdņu disciplināratbildība un tās problemātika”. Šī tēma ir aktuāla, jo ne normatīvais regulējums, ne zinātniskā literatūra nesniedz izsmeļošu visu disciplināratbildības noteikumu aprakstu.
Agapova, Jevgēnija
core  

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

Advanced Science, EarlyView.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang, Yaozhi He, Yanjiao Wang, Jingjing Zhang, Qishun Liang, Mengxian Jia, Yumin Wu, Zongjie Yuan, Ziwei Fan, Yuxuan Li, Huihui Zhang, Qinjiao Fu, Ying Wang, Zhihui Huang, Honglin Teng   +14 more
wiley   +1 more source

PECULIARITIES OF DISCIPLINARY RESPONSIBILITY OF PROSECUTOR'S OFFICIALS

, 2021
Problem setting. Reforming prosecutor legislative establishment in Ukraine, expanding the list of grounds for bringing to disciplinary liability of prosecutors as subjects of labor law leads to new, unresolved issues related to the above circumstances.
openaire   +1 more source