Results 171 to 180 of about 1,210,291 (287)

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Printing knowledge in microgravity: PULSE and the education needed for space biomedicine. [PDF]

Exp Physiol
Baatout S, Candotti M, Tabury K, Baselet B, Bailey DM, Moroni L.   +5 more
europepmc   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

The Impact of a Multi-Source "3 + 1" Feedback Model on Formative Assessment and Student Development in Higher Education: A Case Study in Undergraduate Biochemistry. [PDF]

Biochem Mol Biol Educ
Yan Y.
europepmc   +1 more source

Synergistic Grain Boundary and Phonon Engineering Enables Ultrahigh Thermoelectric Performance in Mg3(Sb, Bi)2‐Based Materials

Advanced Science, EarlyView.
Ta encapsulated melting and Cu doping synergistically engineer grain boundaries and phonon scattering in Mg3(Sb,Bi)2, enabling single‐crystal‐like carrier transport and high thermoelectric performance. ABSTRACT Thermoelectric Mg3(Sb, Bi)2 has emerged as a rising star in virtue of its promising thermoelectric performance and abundant constituent ...
Jingdan Lei, Kai Xu, Kunpeng Zhao, Junzhuo Zhou, Haotian Gao, Yifan Yuan, Tian‐Ran Wei, Min Zhu, Qihao Zhang, Franck Gascoin, Xun Shi   +10 more
wiley   +1 more source

The Code of Silence in Healthcare: Exploratory Cross-National Evidence and a Framework for Reporting and Responsibility. [PDF]

Health Serv Insights
Manev IM, Miaoulis G, Cumpat CM, Theodoru IC.   +3 more
europepmc   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Bioethics and Medical Litigation in France: An Exploratory Study. [PDF]

J Eval Clin Pract
Nader R, Stoeklé HC, Shehba LS, Jazat P, Hervé C.   +4 more
europepmc   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

Advanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu, Shanyao Liu, Haixin Liang, Jiani Yang, Yanhe Li, Jiqing Yin, Xueguang Zhang, Yan Zhang, Dandan Bai, Zihui Yan, Zhuoao Zhang, Yanping Jia, Kuisheng Liu, Yifan Sheng, Jiani Xiang, Chenxiang Xi, Baoxing Dong, Xinyi Lei, Jiayu Chen, Hong Wang, Yi Guo, Yanping Zhang, Shaorong Gao, Wenqiang Liu   +23 more
wiley   +1 more source

Concrete Behaviours Expected in Interdisciplinary Teams in Home Nursing Care Inspired by Buurtzorg: Qualitative Descriptive Study. [PDF]

Scand J Caring Sci
Bøgeskov BO, Segoli G.
europepmc   +1 more source