Results 111 to 120 of about 427,190 (308)
Global Health Action, 2018 Background: Studies examining how the capacity of health facilities affect implementation of free healthcare policies in low and middle-income countries are limited.
Daniel C. Ogbuabor, Obinna E. Onwujekwe
doaj +1 more source
Advanced Science, EarlyView.The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang +12 more
wiley +1 more source
PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury
Advanced Science, EarlyView.Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu +11 more
wiley +1 more source
THE PERSONS DEPRIVED OF LIBERTY, AS PASSIVE SUBJECT OF THE CRIMINAL EXECUTION LEGAL RELATIONSHIPS [PDF]
Challenges of the Knowledge Society, 2019 The study analyzes the behaviour of individuals deprived of their liberty both as an individual phenomenon and in relations established during the execution of custodial sentences.
Simona Cireșica OPRIȘAN
doaj
Enforcing Courtesy: Default Judgments and the Civility Movement [PDF]
, 2000 We have much less of a sense of shared values than we used to have. There was a common understanding of how you acted. You zealously represented your client, but you had respect for the other side and treated them with dignity. Afterward, you\u27d all
Glist, Adam Owen
core +1 more source
Pro‐ATO/Allicin Liposomes for Dual‐Pathway Targeting of p53‐Mutant Tumors
Advanced Science, EarlyView.Schematic illustration of the “pro‐ATO”/allicin liposomal strategy. Liposomal encapsulation improves the stability and bioavailability of both agents while masking allicin's odor. Upon release in the tumor microenvironment, ATO reactivates structural p53 mutants, and allicin inhibits ATR signaling while releasing H2S, collectively inducing synthetic ...
Xiaoling Xu +11 more
wiley +1 more source
CONTRIBUTIONS OF GENDER FOR INCLUSIVE EDUCATION IN SCHOOL GEOGRAPHY
Didáctica Geográfica, 2015 In recent years, the teaching of school geography lived a renewal both in terms of curricular requirements and in the knowledge and practices that go round educational institutions.
MARÍA VICTORIA FERNÁNDEZ CASO +1 more
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Engineering MnPt Bimetallic Nanozymes for Cascade Enzymatic Therapy and Enhanced Radio‐Immunotherapy
Advanced Science, EarlyView.A CD44‐targeted MnPt bimetallic nanozyme (HD@MnO2) integrates multienzyme‐like activity with cGAS–STING activation to boost radio‐immunotherapy. Through cascade biocatalysis, it depletes glutathione, relieves hypoxia, and amplifies ROS, enhancing radiotherapy‐induced DNA damage and immunogenic cell death. The nanozyme promotes dendritic cell maturation
Wenyi Zhang +8 more
wiley +1 more source
LAY JUDGES IN THE DISCIPLINARY CHAMBER OF THE POLISH SUPREME COURT: DISCIPLINARY SANCTIONS TO JUDGES
Jurisprudencija, 2021 Since 2015, the Republic of Poland has been facing serious challenges to the constitutional order of a democratic state governed by the rule of law, which is based on the principle of the separation of powers and their balance. The highest representative body of the nation – the parliament, elected by universal suffrage – adopted amendments to the law ...
openaire +1 more source
Advanced Science, EarlyView.Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan +8 more
wiley +1 more source