Results 111 to 120 of about 81,900 (286)
Advanced Science, EarlyView.This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao +13 more
wiley +1 more source
Tracking Report 2010 Rawlings Sporting Goods, China 11902151066I [PDF]
, 2010 This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Fair Labor Association
core +1 more source
LAY JUDGES IN THE DISCIPLINARY CHAMBER OF THE POLISH SUPREME COURT: DISCIPLINARY SANCTIONS TO JUDGES
Jurisprudencija, 2021 Since 2015, the Republic of Poland has been facing serious challenges to the constitutional order of a democratic state governed by the rule of law, which is based on the principle of the separation of powers and their balance. The highest representative body of the nation – the parliament, elected by universal suffrage – adopted amendments to the law ...
openaire +1 more source
The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer
Advanced Science, EarlyView.In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu +16 more
wiley +1 more source
A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals
Advanced Science, EarlyView.This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao +16 more
wiley +1 more source
Should There Be a Specialized Ethics Code for Death-Penalty Defense Lawyers [PDF]
, 2016 State ethics codes based on the ABA Model Rules of Professional Conduct address lawyers\u27 work in advocacy but do not target lawyers\u27 work in particular areas of advocacy or in other specialized practice areas.
Green, Bruce A.
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Advanced Science, EarlyView.Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang +12 more
wiley +1 more source
Convergence of the Disciplinary Processes of Accounting Organizations? A Comparison Between the United States and France. [PDF]
A number of studies have attempted to compare modes of regulation of the accounting profession in different countries. Because their wide scope, most of these studies don’t achieve the level of insight given by local researches.
Garmilis, Ghislaine, Stokes, Leonard
core
When We Don\u27t See Eye to Eye: Discrepancies Between Supervisors and Subordinates in Absence Disciplinary Decisions [PDF]
, 1992 This study provided a within-subjects assessment of the factors associated with absence disciplinary decisions for both supervisors and subordinates. In addition, this study examined discrepancies in disciplinary decisions between a supervisor and his or
Judge, Timothy A. +1 more
core +1 more source
Intelligent Stain‐Free Histology on Structural Colorimetric Nanocavities
Advanced Science, EarlyView.Chen and Gan et al. introduce a label‐free imaging platform using inexpensive Nanocavity‐on‐Silicon (NOS) slides. These slides transform subtle tissue variations into vivid structural colors, enabling high‐contrast histological imaging under a regular optical microscope. This stain‐free approach reveals morphological details comparable to traditional H&
Qizhe Chen +18 more
wiley +1 more source