Results 91 to 100 of about 381,849 (287)

The EU’s Sanctions against Syria: Conflict Management by Other Means. Security Policy Brief No. 38 [PDF]

open access: yes, 2012
Since May 2011, the EU has launched one of its most far reaching and sophisticated sanctions operations in support of the protests against the current regime in Syria.
Portela, Clara
core   +1 more source

TRIM28‐Derived Peptide Exerts Anti‐Tumor Roles by Stabilizing Tumor Suppressive BRD7 Protein in Multiple Cancers

open access: yesAdvanced Science, EarlyView.
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei   +10 more
wiley   +1 more source

The Impact of Economic Sanctions on US Trade: Andrew Rose's Gravity Model [PDF]

open access: yes
With the end of the Cold War, the focus of US foreign policy changed--and so did that of economic sanctions. Partly because of increased cooperation within the UN framework, economic sanctions were imposed so routinely in the early 1990s that scholars ...
Barbara Oegg, Gary Clyde Hufbauer
core  

Copper‐Doped Prussian Blue Nanozymes With Hyaluronic Acid‐Mediated Targeting Alleviate Oxidative Stress and Regulate Cholesterol Handling for Atherosclerosis Therapy

open access: yesAdvanced Science, EarlyView.
CuPB@HA is a CD44‐associated, plaque‐targeted nanozyme that alleviates oxidative stress, inflammation, and lipid accumulation in macrophages. By reducing CD36‐dependent lipid uptake and promoting ABCA1/ABCG1‐mediated cholesterol handling, it improves macrophage function, preferentially accumulates in atherosclerotic lesions, reduces plaque burden, and ...
Jianliang Ou   +14 more
wiley   +1 more source

العقوبات التأديبية على الموظف الدولي. [PDF]

open access: yesمجلة البحوث القانونية و الاقتصادية
مما لا ريب فيه أن العقوبات التأديبية في القانون الدولي، كانت محور اهتمام فقهاء القانون الدولي على حد سواء، ولعل سبب هذا الاهتمام يعود إلى المقارنة التي يجريها البعض بين العقوبات التأديبية في القانون الدولي، وذلك وفقًا لما تقتضيه المواثيق والاتفاقيات ...
أحمد سلطان عبدالله المهيري
doaj   +1 more source

Should We Set the Market Free? Some Notes on International Economic Sanctions [PDF]

open access: yes
International Political economy, International economic sanctions, international ...
Raul Caruso
core  

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

open access: yesAdvanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun   +12 more
wiley   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi   +7 more
wiley   +1 more source

Japan’s Foreign Aid Sanctions Policy after the End of Cold War [PDF]

open access: yes
During the Cold War, Japan seldom showed an interest in the political conditions in aid recipients. However, after the Cold War, Japan has been actively imposing negative aid sanctions (the suspension or a decrease in foreign aid) on recipient countries ...
Furuoka, Fumitaka, Nikitina, Larisa
core  

A Novel tRNA Half mt‐5’‐tiRNA‐Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation

open access: yesAdvanced Science, EarlyView.
A mitochondria‐derived tRNA half, mt‐5’‐tiRNA‐Tyr, is upregulated in colorectal cancer tissues and plasma and promotes tumor proliferation. It binds HARS2 and promotes CPT1A‐associated HARS2 K91 succinylation, disrupts HARS2–mt‐tRNA‐His association, impairs mitochondrial translation, enhances succinate‐linked metabolic reprogramming, and shows promise ...
Xinliang Gu   +10 more
wiley   +1 more source

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