Results 141 to 150 of about 630,731 (316)

The Letter of Benedict XVI on Education: a guiding light for secularism and Catholicism

open access: yesInternational Journal of Psychoanalysis and Education, 2011
This work analyze the Letter of Pope Benedict XVI on „Educational Emergency’ (2008), that makes it essential for a new thinking on both the secular world and the catholic.
Elvira Lozupone
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The potential role of subordinated debt programs in enhancing market discipline in banking [PDF]

open access: yes
Previous studies have found that subordinated debt (sub-debt) markets do differentiate between banks with different risk profiles. This finding satisfies a necessary condition for regulatory proposals which would mandate increased reliance on sub-debt in
Douglas Evanoff   +2 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Engendering discipline : perceptions and practices of students and teachers in a secondary school in South Africa

open access: yes, 2010
Includes bibliographical references (leaves 97-106).This thesis aimed to investigate whether there is a gender bias in the way teachers discipline boys and girls.
Singh, Marcina
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Discipline diversity and agency : pedagogic practice and dispositions to learning

open access: yes, 2010
What, then, makes discipline good? .. .is not discipline-all discipline-essentially a restraint, a limitation imposed on man's behaviour? If life is good, how can it be good to bridle it, to constrain it, to impose limits that it cannot overcome ...
Watkins, Megan (R10473)
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Response to LTE "Bridging the Gap Between Patient Experience and System-Level Review: A Call for Discipline-Specific Communication in Hospital-to-Home Transitions. [PDF]

open access: yesHealth Expect
van Grootel J   +8 more
europepmc   +1 more source

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