Results 231 to 240 of about 852,357 (308)

How Does the Mental Health Lived Experience Workforce Describe and Enact Our Discipline? A Narrative Literature Review. [PDF]

Health Expect
Roper C, Sharpe S, Azoury L, Joffee-Kohn N, Swingler N, Sansanwal P, McKenner L, Van Remmen C, Hamilton B.   +8 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Interdisciplinary Perspectives on Patient Adherence to Therapy: Findings from a Qualitative Study. [PDF]

Healthcare (Basel)
González-García P, Fernández-Seguín L, Escamilla-Martínez E, Fernández-García E, Gago-Valle C, García-Bernal MI.   +5 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Unique Challenges of Multidisciplinary Clinical Science: Perspectives from a Multidisciplinary Team. [PDF]

Clin Psychol Sci
Pokorny V, Damme K, Haase CM, Goldrick M, Mittal VA.   +4 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Reply to: "The Future of Clinical Pharmacology: The Right Medicine at the Right Dose for Each Patient". [PDF]

Clin Pharmacol Ther
Rizk ML, Visser SAG.
europepmc   +1 more source