Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Artificial intelligence in osteoporosis screening and fracture risk prediction among aging populations: a bibliometric evidence map. [PDF]
Wang B +7 more
europepmc +1 more source
Regulatory Science: exploring an emerging scientific discipline in health care. [PDF]
Volpi L +4 more
europepmc +1 more source
RETRACTED: Wang et al. Integrated Analysis of Physiological and Transcriptional Mechanisms in Response to Drought Stress in <i>Scaevola taccada</i> Seedlings. <i>Plants</i> 2026, <i>15</i>, 970. [PDF]
Wang Y, Liu W, Zuo C, Luo Y, Huang M.
europepmc +1 more source
Family physician versus specialist family physicians: Curse or edge of collapse? [PDF]
Lutala PM +4 more
europepmc +1 more source
Growing a Learning Health Care Community: reflections from the 6for6 rural research journey: Part 1 of a 4-part series. [PDF]
Asghari S +6 more
europepmc +1 more source
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For the present and future happiness of the child, and certainly for the well-being of those about him, the child must learn some obedience. The majority of parents know this, but from time to time may be discouraged and doubtful about their program of discipline. The pediatrician can do a great deal to help.
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Writing for the discipline in the discipline?
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