Results 251 to 260 of about 2,361,739 (390)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Establishing an empirical cut-off on the 12-item Brief Berger HIV Stigma Scale to screen psychosocial vulnerability among PLHIV in Nigeria. [PDF]

PLOS Glob Public Health
Abdulraheem KS, Onajole AT, Roberts AA, Olowoopejo T.   +3 more
europepmc   +1 more source

Evidencing equality: approaches to increasing disclosure and take-up of disabled students’ allowance [PDF]

, 2012
Holland, Robert, Madriaga, Manuel, Stevens, Tony, Waters, Barbara   +3 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Carotenoid Status and Psychological Impact of Presymptomatic Macular Degeneration Genetic Risk Assessment: The MAGENTA Randomized Trial. [PDF]

Ophthalmol Sci
Addo EK, Lucci L, Nilson J, Pasaye M, Pappas C, Spoth E, Ord L, Jridi A, Brintz BJ, Hageman GS, Hartnett ME, Bernstein PS.   +11 more
europepmc   +1 more source

Multivariate Top-Coding for Statistical Disclosure Limitation

, 2020
Anna Oganian, Ionut E. Iacob, Goran Lešaja   +2 more
openalex   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

A proposed ethical framework for informed consent in elective robotic telesurgery. [PDF]

J Robot Surg
Frenkel CH, Moschovas MC, Saikali S, Patel V.   +3 more
europepmc   +1 more source

Perceived Credibility of Children's Sexual Abuse Disclosures: Language Fluency and Contextual Information

Coburn, Patricia I, Hrusheva, Anna
openalex   +1 more source

Agents of empathy: How medical interpreters bridge sociocultural gaps in genomic sequencing disclosures with Spanish-speaking families

, 2018
Amanda M. Gutierrez, Emily E. Statham, Jill O. Robinson, Melody J. Slashinski, Sarah Scollon, Katie Bergstrom, Richard L. Street, D. Williams Parsons, Sharon E. Plon, Amy L. McGuire   +9 more
openalex   +2 more sources