Classifying discoid lupus erythematosus: background, gaps, and difficulties
To inform our ongoing efforts to develop defining features to be incorporated into a novel set of classification criteria for discoid lupus erythematosus (DLE), we conducted a literature review using the Ovid MEDLINE database.
Jessica S. Haber, BA+2 more
doaj
IntroductionDiscoid lupus erythematosus (DLE) is a chronic autoimmune skin disorder. Research fragmentation in DLE limits cohesive clinical and scientific progress.
Daichao Zhang+3 more
doaj +1 more source
Phosphodiesterase 4 in inflammatory diseases: Effects of apremilast in psoriatic blood and in dermal myofibroblasts through the PDE4/CD271 complex [PDF]
Phosphodiesterases 4 (PDE4) act as proinflammatory enzymes via degradation of cAMP, whereas PDE4 inhibitors play an anti-inflammatory role in vitro and in vivo.
Horan, Gerald+11 more
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Discoid lupus erythematosus involving gingiva
Desquamative gingival lesions are non-plaque induced inflammatory gingival lesions. It is a clinical description and not a diagnosis. These desquamative lesions represent oral manifestations of various dermatoses. Discoid lupus erythematosus is one of the rare dermatoses which show desquamative lesions as oral manifestations.
K Kranti, Hema Seshan, J Juliet
openaire +3 more sources
Rowell's syndrome in an Indian male and review of the literature
Lupus erythematosus (LE) with erythema multiforme-like lesions with its characteristic serological picture had been described in 1963. We report a 33-year-old married male who presented with skin lesions of various morphology on different body parts ...
Bhushan Madke, Uday Khopkar
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Cognitive dysfunction improves in systemic lupus erythematosus: Results of a 10 years prospective study [PDF]
Objective Cognitive impairment (CI) has been described in 3–80% of Systemic lupus erythematosus (SLE) patients but only short-term studies evaluated its over-time changes, suggesting that CI is usually a stable finding. We aimed at evaluating the changes
Alessandri, Cristiano+9 more
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Emerging Topical and Systemic JAK Inhibitors in Dermatology [PDF]
Accumulating data on cellular and molecular pathways help to develop novel therapeutic strategies in skin inflammation and autoimmunity. Examples are psoriasis and atopic dermatitis, two clinically and immunologically well-defined disorders.
Ghoreschi, Kamran+2 more
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Lupus erythematosus panniculitis in pregnancy
A case of lupus erythematosus (LE) panniculitis in pregnancy without any lesions of discoid LE or systemic LE is being reported. There were no systemic symptoms.
Swati Gondane+3 more
doaj +1 more source
Mucocutaneous Manifestation of Systemic Lupus Erythematosus Patients at Rheumatology Outpatient Clinic in Dr. Hasan Sadikin General Hospital [PDF]
Background: Systemic Lupus Erythematosus (SLE) is an autoimmune systemic disease which symptoms induced by Ultraviolet rays exposure. It commonly affects women and causes wide range of symptoms. One of the organs affected is mucocutaneous. Our study aims
Dharmadji, H. P. (Hartati)+3 more
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The prevalence of anti-C1q antibodies in black South Africans with systemic lupus erythematosus and their clinical significance [PDF]
INTRODUCTION: Several studies have shown an association of anti-C1q antibodies (abs) with systemic lupus erythematosus (SLE) nephritis and disease activity.
Makda, Mohamed Amin
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