Results 61 to 70 of about 127,925 (265)

Evidence for a Pathophysiological Role of Keratinocyte-Derived Type III Interferon (IFNλ) in Cutaneous Lupus Erythematosus [PDF]

, 2011
Type I IFNs (IFNα/β) have been shown to have a central role in the pathophysiology of lupus erythematosus (LE). The recently discovered type III IFNs (IFNλ1/IL29, IFNλ2/IL28a, IFNλ3/IL28b) share several functional similarities with type I IFNs ...
Bieber, Thomas, Ferring-Schmidt, Sandra, Kümmerer, Beate M., Rehkämper, Claudia, Tüting, Thomas, Wenzel, Jörg, Zahn, Sabine   +6 more
core   +1 more source

Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti–Interferon‐γ Antibody, in Patients With Discoid Lupus Erythematosus

Arthritis & Rheumatology, 2017
Interferon‐γ (IFNγ) is implicated in the pathogenesis of discoid lupus erythematosus (DLE). This study sought to evaluate a single dose of AMG 811, an anti‐IFNγ antibody, in patients with DLE.
V. Werth, D. Fiorentino, B. Sullivan, M. Boedigheimer, Kit Chiu, Christine Wang, G. E. Arnold, M. Damore, J. Bigler, A. Welcher, C. Russell, David A. Martin, J. Chung   +12 more
semanticscholar   +1 more source

Antimalarials and the eye [PDF]

, 1989
Following the first reports in 1954 of the beneficial effects of chloroquine in cases of lupus erythematosus, this drug and its numerous derivatives have been used extensively in the treatment of systemic and discoid lupus erythematosus and rheumatoid ...
Coleiro, Joseph A.
core  

Successful use of anifrolumab in refractory cutaneous lupus erythematosus with systemic lupus erythematosus: A case report

SAGE Open Medical Case Reports
A 61-year-old female with systemic lupus erythematosus presented with refractory discoid lupus. Despite treatment with numerous immunosuppressive therapies, including prednisone, hydroxychloroquine and mycophenolate mofetil, her cutaneous lupus remained ...
Abdullah Ramadhan, Anita Troug, Elaine Yacyshyn, Robert Gniadecki   +3 more
doaj   +1 more source

Effects of mycophenolate mofetil on cutaneous lupus erythematosus in (NZB × NZW) F1 mice [PDF]

, 2006
BackgroundFew studies have evaluated the effects and precise molecular mechanism of mycophenolate mofetil (MMF) in the treatment of human cutaneous lupus erythematosus (CLE). Our findings shed light on the therapeutic effects of MMF in a UVB-induced NZB ×
Lee, Yen-Feng, Cheng, Ching-Chang, Lan, Joung-Liang, Hsieh, Tsu-Yi, Lin, Nai-Nu, Lin, Hui-Ying, Chiu, Yung-Tsung   +6 more
core   +2 more sources

Treatment of Lupus Erythematosus of the Eyelids with Pulsed Dye Laser [PDF]

, 2016
info:eu-repo/semantics ...
Boixeda, P, Brás, S, Gonzalez, B, Segurado-Miravalles, G   +3 more
core   +1 more source

Neonatal Lupus Erythematosus: New Serologic Findings [PDF]

, 1981
A child with neonatal lupus was evaluated and found to possess serum anti Ro(SSA) antibodies. The cutaneous lesions and anti Ro(SSA) antibodies disappeared during the next 5 mo.The infant's mother was asymptomatic but possessed anti Ro(SSA) and anti La ...
Hood, Antoinette F., Kephart, Dale C., Provost, Thomas T.   +2 more
core   +1 more source

Vulgar psoriasis and squamous cell carcinoma in a patient with discoid lupus erythematosus

Vestnik Dermatologii i Venerologii, 2020
A rare case of a combination of vulgar psoriasis and squamous cell carcinoma of the penis in a patient with discoid lupus erythematosus is described. The literature data on the comorbidity of dermatoses are given.
Valeriy V. Dubensky, Elizaveta G. Nekrasova, Olga A. Alexandrova, Ekaterina S. Muraveva   +3 more
doaj   +1 more source

Developing classification criteria for discoid lupus erythematosus: an update from the World Congress of Dermatology 2015 meeting

International Journal of Women's Dermatology, 2016
Currently, no standardized classification criteria exist for cutaneous lupus erythematosus. With increased interest in studying cutaneous lupus erythematosus, specifically discoid lupus erythematosus, it is our aim to apply previously adopted methods ...
Scott A. Elman, AB, Filippa Nyberg, MD, Fukumi Furukawa, MD, Mark Goodfield, MD, Minoru Hasegawa, MD, Branka Marinovic, MD, Jacek Szepietowski, MD, Jan Dutz, MD, FRCPC, Victoria P. Werth, MD, Joseph F. Merola, MD, MMSc   +9 more
doaj  

Current treatment strategies: Collagen vascular diseases in children

Indian Journal of Dermatology, 2012
Of the various collagen vascular diseases seen in pediatric age group, discoid lupus erythematosus, systemic lupus erythematosus, neonatal lupus erythematosus, juvenile dermatomyositis and childhood scleroderma are common and of practical importance to ...
Aparna Palit, Arun C Inamadar
doaj   +1 more source