Results 61 to 70 of about 7,425 (229)

MIRACLE: Multi-task Learning based Interpretable Regulation of Autoimmune Diseases through Common Latent Epigenetics [PDF]

arXiv, 2023
DNA methylation is a crucial regulator of gene transcription and has been linked to various diseases, including autoimmune diseases and cancers. However, diagnostics based on DNA methylation face challenges due to large feature sets and small sample sizes, resulting in overfitting and suboptimal performance. To address these issues, we propose MIRACLE,
arxiv  

Off‐Label Use of Topical Ruxolitinib in Dermatology: A Systematic Literature Review and Current Perspectives

Experimental Dermatology, Volume 34, Issue 4, April 2025.
ABSTRACT JAK inhibitors are used to treat various inflammatory skin diseases. However, systemic formulations are associated with an increased risk of major adverse events. Ruxolitinib 1.5% cream is a selective topical JAK1 and JAK2 inhibitor, which has recently been approved by EMA and MHRA for treating non‐segmental vitiligo, while being FDA‐approved ...
Marco Spadafora, Serena Morsia, Vito Giuseppe Di Lernia, Shaniko Kaleci, Giovanni Pellacani, Caterina Longo   +5 more
wiley   +1 more source

Lúpus comedônico: rara apresentação do lúpus eritematoso discoide Comedonic lupus: a rare presentation of discoid lupus erythematosus

Anais Brasileiros de Dermatologia, 2011
Lúpus eritematoso cutâneo crônico é doença autoimune, com apresentações polimorfas que podem, eventualmente, mimetizar outras condições clínicas, causando dificuldade diagnóstica.
Daniela Ferro Farias, Roberta Marinho Falcão Gondim, Isabella Portela Redighieri, Helena Muller, Valéria Petri   +4 more
doaj   +1 more source

Systemic lupus erythematosus in African-American women: Cognitive physiological modules, autoimmune disease, and structured psychosocial stress [PDF]

arXiv, 2003
Examining elevated rates of systemic lupus erythematosus in African-American women from perspectives of immune cognition suggests the disease constitutes an internalized physiological image of external structured psychosocial stress, a 'pathogenic social hierarchy' involving the synergism of racism and gender discrimination in the context of policy ...
arxiv  

The Need to Improve the Medical Subject Headings (MeSH) and the Excerpta Medica Tree (EMTREE) Thesauri to Perform Systematic Review on Oral Potentially Malignant Disorders

Journal of Oral Pathology &Medicine, Volume 54, Issue 4, Page 241-247, April 2025.
ABSTRACT Background Despite recent advancements in the understanding and classification of oral potentially malignant disorders (OPMD), their terminology remains inconsistent and heterogeneous throughout the scientific literature, thus affecting evidence‐based decision‐making relevant for clinical management of these disorders.
Vito Carlo Alberto Caponio, Gennaro Musella, Mario Pérez‐Sayáns, Lorenzo Lo Muzio, Rui Amaral Mendes, Rosa María López‐Pintor   +5 more
wiley   +1 more source

Current Insights Into The Management Of Discoid Lupus Erythematosus

Clinical, Cosmetic and Investigational Dermatology, 2019
Jaime Company-Quiroga,* Sergio Alique-García,* Alberto Romero-MatéDermatology Department, Fuenlabrada Univesity Hospital, Madrid, Spain*These authors contributed equally to this workCorrespondence: Jaime Company-QuirogaDermatology ...
Company-Quiroga J, Alique-García S, Romero-Maté A   +2 more
doaj  

Drug History and SLE Laboratory Findings Among Iraqi Patients: A Hospital‐Based Study

Health Science Reports, Volume 8, Issue 3, March 2025.
ABSTRACT Background and Aims Systemic lupus erythematosus (SLE) is a recurrent and remitting autoimmune disease that affects many organ systems. It is more common in women of reproductive age, with a 9:1 female preponderance. Due to the lack of data from developing countries, our study aims to provide comprehensive insights into the drug history and ...
Hashim Talib Hashim, Ahmed Dheyaa Al‐Obaidi, Mustafa Najah Al‐Obaidi, Hossam Tharwat Ali, Idris Sula, Hozifa Alfaki, Abdelrahim Elamin, Alaa Hamza Hermis, Assalah Othman, Ahmed Qasim Mohammed Alhatemi   +9 more
wiley   +1 more source

Wound, pressure ulcer, and burn guidelines (2023)―4: Guidelines for the management of connective tissue disease/vasculitis‐associated skin ulcers, third edition

The Journal of Dermatology, EarlyView.
Yoshihide Asano, Jun Asai, Takayuki Ishii, Yohei Iwata, Masanari Kodera, Chie Miyabe, Akihiko Uchiyama, Youichi Ogawa, Ken Okamura, Mari Kishibe, Yuta Koike, Yorihisa Kotobuki, Noriki Fujimoto, Takuya Miyagi, Yukie Yamaguchi, Ayumi Yoshizaki, Reiko Omori, Takeshi Nakanishi, Hiroshi Fujiwara, Takeo Maekawa, Sei‐ichiro Motegi, Yuichiro Yoshino, Minoru Hasegawa, Manabu Fujimoto, Takao Tachibana, Wound, Pressure Ulcer, and Burn Guidelines Drafting Committee (connective tissue disease/vasculitis group)   +27 more
wiley   +1 more source

Analysing referral patterns from a primary dermatological clinic to other medical institutions for further care: A survey on patients with certain skin diseases in Japan

JEADV Clinical Practice, Volume 4, Issue 1, Page 181-187, March 2025.
Abstract Background Various skin diseases exist; some require specialist treatment. Consequently, patients with these conditions are often referred from primary dermatological clinics to other medical institutions for further secondary or tertiary care.
Daisuke Ueo, Takashi Sakai, Erika Ochiai, Jun Sese, Yutaka Hatano   +4 more
wiley   +1 more source

Classifying discoid lupus erythematosus: background, gaps, and difficulties

International Journal of Women's Dermatology, 2016
To inform our ongoing efforts to develop defining features to be incorporated into a novel set of classification criteria for discoid lupus erythematosus (DLE), we conducted a literature review using the Ovid MEDLINE database.
Jessica S. Haber, BA, Joseph F. Merola, MD, MMSc, Victoria P. Werth, MD   +2 more
doaj