Results 91 to 100 of about 591,464 (366)

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

Clinical consultations and investigations before and after discontinuation of endocrine therapy in women with primary breast cancer [PDF]

open access: yes, 2017
Objective: Although clinical trials recommend that women with hormone-dependent primary breast cancer remain on endocrine therapy for at least 5 years, up to 60% discontinue treatment early. We determined whether these women had consulted with clinicians
David Preen   +13 more
core   +1 more source

Designing Discontinuities

open access: yes
Abstract Discontinuities can be fairly arbitrary but also cause significant impacts on outcomes in larger systems. Indeed, their arbitrariness is why they have been used to infer causal relationships among variables in numerous settings. Regression discontinuity from econometrics assumes the existence of a discontinuous variable, a threshold ...
Ibtihal Ferwana   +3 more
openaire   +2 more sources

Business Restart in Visegrad Countries

open access: yesEntrepreneurial Business and Economics Review, 2014
The main goal of our paper is to analyse business restarts in Visegrad countries on an individual level and to identify key drivers of restart activity from among perceptual variables. The analysis is based on Global Entrepreneurship Monitor data.
Marian Holienka   +2 more
doaj   +1 more source

Factors that influence adolescent girls and young women's re‐initiation or complete discontinuation from daily oral PrEP use: a qualitative study from Eastern Cape Province, South Africa

open access: yesJournal of the International AIDS Society, 2023
Introduction Adolescent girls and young women (AGYW) face barriers that jeopardize their prevention‐effective use of daily oral pre‐exposure prophylaxis (PrEP). We sought to understand factors that influence AGYW's prolonged breaks in PrEP use, and their
Lindsey deVos   +10 more
doaj   +1 more source

Risk factors for discontinuation of buprenorphine treatment for opioid use disorders in a multi-state sample of Medicaid enrollees

open access: yesJournal of Substance Abuse Treatment, 2018
Introduction: Recent U.S. trends demonstrate sharp rises in adverse opioid-related health outcomes, including opioid use disorder (OUD), overdose, and death.
Hillary Samples   +3 more
semanticscholar   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Blue again: Perturbational effects of antidepressants suggest monoaminergic homeostasis in major depression

open access: yesFrontiers in Psychology, 2011
Some evolutionary researchers have argued that current diagnostic criteria for major depressive disorder (MDD) may not accurately distinguish true instances of disorder from a normal, adaptive stress response.
Paul eAndrews   +5 more
doaj   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer   +11 more
wiley   +1 more source

Discontinuation symptoms associated with nefazodone

open access: yes, 2003
PubMedID: 14870958We present a patient who developed discontinuation symptoms following abrupt cessation of nefazodone. Three days after the first appearance of the discontinuation symptoms (i.e. 5 days after cessation of the drug), all symptoms resolved
Ozpoyraz N., Tamam L.
core   +1 more source

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