Results 81 to 90 of about 591,464 (366)

On the discontinuity of the π1-action [PDF]

open access: yesTopology and its Applications, 2018
We show the classical $π_1$-action on the $n$-th homotopy group can fail to be continuous for any $n$ when the homotopy groups are equipped with the natural quotient topology. In particular, we prove the action $π_1(X)\timesπ_n(X)\toπ_n(X)$ fails to be continuous for a one-point union $X=A\vee \mathbb{H}_n$ where $A$ is an aspherical space such that ...
openaire   +2 more sources

Acute Care, Prescription Opioid Use, and Overdose Following Discontinuation of Long-Term Buprenorphine Treatment for Opioid Use Disorder

open access: yesAmerican Journal of Psychiatry, 2019
Objective: Although buprenorphine treatment reduces risk of overdose and death in opioid use disorder, most patients discontinue treatment within a few weeks or months.
A. Williams   +3 more
semanticscholar   +1 more source

Patient characteristics and outcomes after ruxolitinib discontinuation in patients with myelofibrosis

open access: yesJournal of Medical Economics, 2020
Background: This retrospective analysis evaluates morbidities, outcomes and associated risk factors in patients with myelofibrosis (MF) after ruxolitinib discontinuation, using Truven Health Analytics MarketScan (TR), Optum integrated virtual electronic ...
J. Mascarenhas   +4 more
semanticscholar   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Discontinuation events.

open access: yes, 2013
Data are presented as number of discontinuation events with annual probability of discontinuation stratified by recorded reasons for discontinuation. The events were recorded in all patients within the MSBase ever treated with Rebif.
Francois Grand’Maison (301649)   +50 more
core   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji   +13 more
wiley   +1 more source

Feasibility of Discontinuing Biologics in Severe Asthma: An Algorithmic Approach

open access: yesJournal of Asthma and Allergy, 2021
Kazuki Hamada,1 Keiji Oishi,2 Yoriyuki Murata,2 Tsunahiko Hirano,1 Kazuto Matsunaga1 1Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Yamaguchi, Japan; 2Department of Medicine and ...
Hamada K   +4 more
doaj  

Tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia: a single-institution experience

open access: yesJournal of Hematology & Oncology, 2019
BackgroundPatients with CML treated with TKI can have a life expectancy comparable to that of the general population. Due to the extended duration of TKI administration, treatment discontinuation has been increasingly sought.MethodsMedical records of 100
K. Chamoun   +16 more
semanticscholar   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

Real world hybrid closed-loop discontinuation: Predictors and perceptions of youth discontinuing the 670G system in the first 6 months

open access: yesPediatric Diabetes, 2019
To describe predictors of hybrid closed loop (HCL) discontinuation and perceived barriers to use in youth with type 1 diabetes.
Laurel H. Messer   +7 more
semanticscholar   +1 more source

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