Results 41 to 50 of about 459,789 (287)

Persistencia de medicamentos biológicos durante ocho años en pacientes con artritis reumatoide y espondiloartritis [PDF]

, 2019
Objective: To calculate the persistence, over a period of eight years, the retention rate of first and second-line of treatment with biological agents in patients with rheumatoid arthritis, spondyloarthritis and psoriatic arthritis and to compare ...
Balsa, Alejandro, González-Fernández, María, Herrero, Alicia, Jiménez-Nácher, Inmaculada, Moreno, Francisco, Villamañán, Elena   +5 more
core   +3 more sources

Discontinuities without discontinuity: The Weakly-enforced Slip Method [PDF]

Computer Methods in Applied Mechanics and Engineering, 2014
Submitted for publication in ...
Zwieten, van, G.J., Brummelen, van, E.H., Zee, van der, K.G., Gutiérrez, M.A., Hanssen, R.F.   +4 more
openaire   +4 more sources

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Intentional and non-intentional non-adherence to medication amongst breast cancer patients [PDF]

, 2005
This study aimed to investigate the prevalence of and factors associated with non-adherence to medication amongst a sample of breast cancer patients. 131 women with stable disease were interviewed and completed standardised psychological measures. 55% of
Demissie, Elwyn, Fallowfield, Fallowfield, Farmer, Fellowes, Fink, Grunfeld, Haynes, Horne, Iihara, Lesley Fallowfield, Louise Atkins, McDonald, Partridge, Partridge, Powles, Wallston   +17 more
core   +1 more source

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Variation in seizure risk increases from antiseizure medication withdrawal among patients with well‐controlled epilepsy: A pooled analysis

Epilepsia Open
Objective Guidelines suggest considering antiseizure medication (ASM) discontinuation in seizure‐free patients with epilepsy. Past work has poorly explored how discontinuation effects vary between patients.
Samuel W. Terman, Geertruida Slinger, Adriana Koek, Jeremy Skvarce, Mellanie V. Springer, Julie M. Ziobro, James F. Burke, Willem M. Otte, Roland D. Thijs, Morten I. Lossius, Anthony G. Marson, Laura J. Bonnett, Kees P. J. Braun   +12 more
doaj   +1 more source

‘I just thought that it was such an impossible thing’: A qualitative study of barriers and facilitators to discontinuing long‐term use of benzodiazepine receptor agonists using the Theoretical Domains Framework

Health Expectations, 2022
Introduction Existing interventions to reduce long‐term benzodiazepine receptor agonist (BZRA) use lack theoretical underpinning and detailed descriptions.
Tom Lynch, Cristín Ryan, Cathal A. Cadogan   +2 more
doaj   +1 more source

Safety and Acceptability of Community-Based Distribution of Injectable Contraceptives: A Pilot Project in Mozambique. [PDF]

, 2016
Mozambique has witnessed a climbing total fertility rate in the last 20 years. Nearly one-third of married women have an unmet need for family planning, but the supply of family planning services is not meeting the demand. This study aimed to explore the
Bique, Cassimo, Blazer, Cassandra, Jacinto, Ana, Mobaracaly, Mahomed, Prata, Ndola, Ustáb, Momade, Weidert, Karen   +6 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A primary care, multi-disciplinary disease management program for opioid-treated patients with chronic non-cancer pain and a high burden of psychiatric comorbidity [PDF]

, 2005
BACKGROUND: Chronic non-cancer pain is a common problem that is often accompanied by psychiatric comorbidity and disability. The effectiveness of a multi-disciplinary pain management program was tested in a 3 month before and after trial.
A Rosenblum, AK Burton, AM Elliott, B McCarberg, B Meier, C Maier, CA Hammett-Stabler, CA Soderstrom, CD DeAngelis, CS Cleeland, CS Cleland, CS Cleland, D Bloodsworth, D Fujimoto, DA Fishbain, DA Regier, Darren A DeWalt, DC Turk, DC Turk, DE Joranson, DE Joranson, DE Moulin, DE Weissman, DG Rischitelli, DJ Kavanagh, H Flor, H Ghodse, H McQuay, J Gardner-Nix, J Porter, J Stephen Perhac, JD Bartleson, JD Clark, JE Veney, JK Iglehart, JM Harris Jr, JM Romano, JT Chibnall, JT Farrar, Katherine M Felix, KB Wells, L Allan, L Peters, L Radloff, L Webb, LH Pengel, LK Mannix, M van Tulder, Mary E Bryant, MC Reid, MC Rowbotham, ME Geisser, MF Ballesteros, MI Donovan, Michael P Pignone, MJ Bair, MJ Bair, NG Hoffmann, NJ Adams, OxyContin®, P Belluck, PA Hill, Paul R Chelminski, PE Greenberg, R Colvin, R Friedman, R Melzack, R Rothman, RA Deyo, RB Lipton, RB Lipton, RC Tait, RH Fletcher, RK Portenoy, RK Portenoy, RK Portenoy, RN Jamison, RN Jamison, Robert M Malone, RS Epstein, SA Dunbar, SD Passik, SG Gelfand, SH Roth, SM Fishman, SR Savage, SR Ytterberg, Steven D Prakken, T Bodenheimer, T Bodenheimer, T Bodenheimer, Thomas M Miller, Timothy J Ives, W Arkinstall, WF Stewart, Y Olsen   +95 more
core   +4 more sources