Results 111 to 120 of about 1,570,418 (352)

Linguistic Tests for Discourse Relations

open access: yes, 2013
Discourse structure and discourse relations are an important ingredient in systems for the analysis of text that go beyond the boundary of single clauses.
Versley, Yannick, Gastel, Anna
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Saadi and the modern discourse of Iran [PDF]

open access: yesتاریخ ادبیات, 2011
Aside from the aesthetic aspect of Saadi's works, which has caused him to be referred to as a master, Iranians for many centuries accepted this poet as their moral and wisdom teacher.
عیسی امن خانی   +1 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Discourse Lab jetzt auf Hypotheses / Discourse Lab now on Hypotheses

open access: yes, 2015
[English version below] Discourse Lab postet jetzt aktuelle Ereignisse, Projekte und Ankündigungen auf Hypotheses.org. Wir freuen uns auf eine rege Diskussion unserer Beiträge!
Marcus Mueller
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Globalization, Transition and the Discourse of Management [PDF]

open access: yes
Globalization is a heavily debated phenomenon and can be studied from many perspectives. In the present paper the perspective of the discourse of management is presented.
Suzana Sedmak, Tonci Ante Kuzmanic
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Intonation and discourse : biased questions

open access: yes, 2008
This paper surveys a range of constructions in which prosody affects discourse function and discourse structure.We discuss English tag questions, negative polar questions, and what we call “focus” questions.
Asher, Nicholas, Reese, Brian
core  

Discourse Semantics [PDF]

open access: yes, 2006
Discourse semantics (DSx) is based on the fact that the interpretation of uttered sentences is dependent on and co-determined by the information stored in a specialized middle-term cognitive memory called discourse domain (D). DSx studies the structure and dynamics of Ds and the conditions to be fulfilled by D for proper interpretation.
openaire   +3 more sources

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