Results 91 to 100 of about 137,620 (287)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
, 2006 It is difficult to give a single definition of Critical or Discourse Analysis as a research method. Discourse Analysis can be characterized as a way of approaching and thinking about a problem.nbsp; Discourse Analysis will enable to reveal the hidden motivations behind a text or behind the choice of a particular method of research to interpret that ...
openaire +3 more sources
Institutional discourse analysis: educational discourse
Russian journal of linguistics: Vestnik RUDN, 2009 The author examines discourse parameters for the administrative, teachers and students discourse varieties in American high school. The study identifies the discourse markers, their relationships and functions.
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Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Rhétorique administrative, stratégies discursives et mauvaise nouvelle
Discourse and Writing/Rédactologie, 1996 Céline Beaudet
doaj +1 more source
The Representation Ahok’s Leadership Style in The Jakarta Post News: Critical Discourse Analysis
, 2018 Novia Resti Junaidi +2 more
openalex +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Teaching Procedure Writing: A Lesson Plan
Discourse and Writing/Rédactologie, 1989 M.T (Jean) Dohaney
doaj +1 more source