Results 141 to 150 of about 370,470 (313)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Cortesía lingüística: un estudio en el ámbito educativo
Huarte de San Juan. Filología y Didáctica de la Lengua, 2014 Aunque la cortesía lingüística sea algo muy analizado en adultos, no ha sido investigada en el ámbito educativo. Este estudio pretende señalar y justificar la necesidad de educar a los jóvenes de secundaria en cortesía lingüística.
Iñigo Alduntzin García
doaj
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Revisión y recepción de la retroalimentación en Lengua Española para maestros. Estudio comparativo
Huarte de San Juan. Filología y Didáctica de la Lengua, 2015 El estudio analiza cómo reciben, valoran y aprovechan los estudiantes la revisión de sus producciones escritas por parte del profesor en una asignatura de educación lingüística.
Elia Saneleuterio
doaj
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Looking for Austen in the 21st Century: from Pride and Prejudice to The Lizzie Bennet Diaries
Huarte de San Juan. Filología y Didáctica de la Lengua, 2015 Jane Austen y su obra han sido parte del canon desde principios del siglo XX, pero Austen como fenómeno popular y cultural datan esto en 1995 debido al estreno de la adaptación de la BBC de Orgullo y prejuicio.
Noelia Mª Galán Rodríguez
doaj
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
La tierna mediocridad de los personajes en "Cuentos de verdad" de Medardo Fraile
Huarte de San Juan. Filología y Didáctica de la Lengua, 1995 En este trabajo se analizan los catorce cuentos de Medardo Fraile publicados en el volumen "Cuentos de verdad". El autor con una perspectiva profundamente humana y sensible nos presenta a sus personajes acosados por el mundo exterior, frágiles, pasivos ...
Lucila Estévez Barbolla
doaj
Sara Mills offers an accessible and comprehensive analysis of the term 'discourse' and explores the theoretical assumptions underlying it. This handy, easy to follow pocket guidebook for students provides:* straightforward working definitions* historical
Mills, Sara.
core