Results 151 to 160 of about 370,470 (313)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Xuarben (Ultzaman) aurkitutako sermoiak

Huarte de San Juan. Filología y Didáctica de la Lengua, 1999
Este artículo tiene como objeto sacar a la luz varios sermones recogidos en la parroquia de Xuarbe (Ultzama), que son complemento de otros anteriores publicados por José María Satrústegui.
Orreaga Ibarra Murillo
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A Critical Discourse Analysis of Indigenization in Saskatchewan's Undergraduate Nursing Programs. [PDF]

Nurs Inq
Essien D.
europepmc   +1 more source

The Discourse of Management and the Management of Discourse [PDF]

Discourse is a pervasive tool of management; one might even say that discourse is what managers do. A widespread assumption among managers is that discourse is not only a pervasive tool, but an effective one for precise communication of information, for ...
Mahoney, Joseph T., Connell, Jeanne M., Bruce, Bertram C., Higgins, Chris   +3 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The Roles and Purposes of Caring Touch in Health Professional Practice: A Discourse Analysis. [PDF]

Nurs Inq
Power N, Fadyl J, Walters S, Payne D.
europepmc   +1 more source

A DISCOURSE ANALYSIS OF THE HUMOR DISCOURSE

Travessias, 2011
A linguagem humana mais do que instrumento de comunicao em sua funo expressiva configura-se como meio onde emergem e se produzem significados, cultura e subjetividade. Com essa afirmao sinalizamos que entendemos a linguagem como transpassando a condio de representao e intermediao das relaes do homem com a natureza e com outros homens, indo condio de ...
openaire   +2 more sources

Problems with the critical posture? Foucault and critical discourse analysis

, 2006
This paper provides a brief analysis of Michel Foucault’s work on power and governmentality, and mounts the argument that the treatment of these concepts by Foucault is theoretical rather than empirical or historical.
Kendall, G., Wickham, G.
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source