Results 171 to 180 of about 24,207,407 (408)

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

ESURF: Simple and Effective EDU Segmentation [PDF]

open access: yesarXiv
Segmenting text into Elemental Discourse Units (EDUs) is a fundamental task in discourse parsing. We present a new simple method for identifying EDU boundaries, and hence segmenting them, based on lexical and character n-gram features, using random forest classification.
arxiv  

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Masculine Defaults via Gendered Discourse in Podcasts and Large Language Models [PDF]

open access: yesarXiv
Masculine defaults are widely recognized as a significant type of gender bias, but they are often unseen as they are under-researched. Masculine defaults involve three key parts: (i) the cultural context, (ii) the masculine characteristics or behaviors, and (iii) the reward for, or simply acceptance of, those masculine characteristics or behaviors.
arxiv  

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