Results 91 to 100 of about 17,397 (285)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
CONFORMITY TOWARDS LOCAL WISDOM AMONG THE SAME INDIGENOUS LANGUAGE SPEAKERS [PDF]
, 2013 Speakers of same indigenous language usually share the same values and norms among them. This phenomenon can be searched in Indonesian Chinese society, who is divided in several groups based on their indigenous languages.
Chiakrawati, Swany
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
ASPECTUAL INFLUENCE ON TEMPORAL RELATIONS: A CASE STUDY OF THE EXPERIENTIAL GUO IN MANDARINE [PDF]
Taiwan Journal of Linguistics, 2009 This paper examines how the temporal relation between a clause containing the experiential guo and an adjacent clause is determined. Mandarin is a language not morphologically marked for tenses (e.g., Lin 2006), and therefore, tenses cannot help in ...
Jiun-Shiung Wu
doaj
KO AND RIKA IN JAVANESE OF TEGAL [PDF]
, 2013 Javanese has a variety of dialects and one of them is the one spoken in Tegal and its surrounding regions such as Pemalang and Brebes. The language variation used in the region is characterized, among others, by the pronunciation of some words which ...
Mualimin, Mualimin
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Semi-logical Argumentation Techniques in the Diwan Salat al-Nar by Nabila al-Khatib Based on Dec row’s Views [PDF]
دراسات في اللغة العربيّة وآدابهاQuasi-logical argumentation is one of the most prominent methods used in literary discourse to persuade the recipient. It relies on linguistic and inferential techniques that enhance the strength of an argument, beyond being limited to formal logic alone.
Jamal Ghafeli, Alireza Perizan
doaj +1 more source
LOCAL WISDOM IN JAVANESE PROVERBS (A COGNITIVE LINGUISTIC APPROACH) [PDF]
, 2013 Proverbs are expressions representing views and values in creating harmonious and successful life. This paper is to investigate the local wisdom in Javanese proverbs. Nonparticipant observation method with note-taking technique is used to collect the
Nirmala, Deli
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DISCOURSE CONNECTORS IN THE ESP STUDENTS’ WRITINGS: A PRELIMINARY STUDY
Esteem Journal of English Education Study ProgrammeCohesion and coherent writing are important aspects of a well-written paragraph. For a paragraph to successfully communicate its meaning, it must be coherent and cohesive. Examining how English for Specific Purposes (ESP) students use discourse connectors in their writing was the aim of this study.
openaire +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source