Results 151 to 160 of about 7,271 (262)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Conversational Topic Shifts and Topic Maintenance in Autistic and Neurotypical Children. [PDF]

Autism Res
Ábalos Z, Kissine M, Vicente A, Castroviejo E.   +3 more
europepmc   +1 more source

A study of vietnamese discourse markers in comparison with related french discourse markers

, 2015
This thesis puts forward a study of eleven discourse markers (DM) in vietnamese based on the framework developped by Vu Thi & Paillard (2012) taking into account the form, the scope, the discursive orientation and the semantic value. This analysis results in a distinction between three types of DM in vietnamese those introducing a point of view on the ...
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Combining psychoanalytic concepts and computer science methodologies: an empirical study of the relationship between emotions and the Lacanian discourses. [PDF]

Front Psychol
Gadalla M, Nikoletseas S, Amazonas JRA.
europepmc   +1 more source

Discourse Particles as Speech Act Markers [PDF]

Journal for Language Technology and Computational Linguistics, 2000
openaire   +3 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Reporting verbs across genre sets and research paradigms: a corpus-based analysis of denotation and evaluation in applied linguistics research articles. [PDF]

Front Psychol
Deng L, Li X.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Syntactic change in diachrony versus contact-induced change: two sides of the same coin? [PDF]

Linguist Rev
D'Alessandro R, Putnam MT, Terenghi S.
europepmc   +1 more source