Results 131 to 140 of about 11,180 (306)

Introducing a new entity into discourse: comprehension and production evidence for the status of dutch er ‘‘there” as a higher-level expectancy monitor

open access: yes, 2009
This paper reports on the ways in which new entities are introduced into discourse. First, we present the evidence in support of a model of indefinite reference processing based on three principles: the listener’s ability to make predictive inferences in
Brysbaert, M.   +9 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Recontextualizing and reconceptualizing EU institutional discourse on immigrant integration

open access: yes, 2013
This study aims to carry out an analysis of processes of ‘re-scaling’ of EU institutional discourse in the dissemination of knowledge on immigrant integration as “particular and diverse ways of representing aspects of the world”.
G. D’Acquisto, POLESE, VANDA
core  

Yeah-No: a discourse marker in Australian English [PDF]

open access: yes, 2007
© 2007 Erin Moore.The aim of this study is to investigate the use of yeah-no in English, primarily in Australian English. It is a corpus based study which uses natural language data to analyse the distribution and the function of the discourse marker ...
MOORE, ERIN
core  

Exploring the Fuzzy Boundaries of Discourse Markers Through Manual and Automatic Annotation

open access: yes, 2019
Discourse markers are non-propositional linguistic items that are notoriously difficult to identify as well as to categorize. We can observe several borderline phenomena and overlaps with other formal and functional categories, for example inserts ...
Péter B. Furkó, Furkó Bálint Péter
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Discourse Functions of Chinese Complementizer and Discourse Marker Shuo

open access: yes, 2011
[[abstract]]The present study aims to examine the discourse functions of Chinese complementizer and discourse marker shuo. Previous studies have argued that in many languages the use of different complementizers yields different interpretations of the ...
Hsin-Hua Aaron Chen, 陳信華
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Discourse Across Languages and Cultures

open access: yes
This volume brings together for the first time research by linguists working in cross-linguistic discourse analysis and by second language researchers working in the contrastive rhetoric tradition.
Moder, Carol Lynn.   +1 more
core  

Home - About - Disclaimer - Privacy