Results 91 to 100 of about 1,858,196 (253)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Explorations at the discourse level: Basic Discourse Units, Discourse Markers, and more
, 2016 In this talk I will give an overview of my work on spoken discourse segmentation and on discourse markers in order to explore further research avenues about what is so specific about the discourse level, i.e.
Degand, Liesbeth +1 more
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Annotating discourse connectives by looking at their translation: The translation-spotting technique [PDF]
, 2013 The various meanings of discourse connectives like while and however are difficult to identify and annotate, even for trained human annotators. This problem is all the more important that connectives are salient textual markers of cohesion and need to be
Cartoni, Bruno +2 more
core +3 more sources
Grammaticalization of discourse markers: views from Jordanian Arabic. [PDF]
Heliyon, 2021 Jaradat A, Jaradat A.
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Semantics and Pragmatics of Discourse Markers [PDF]
This chapter deals with the semantic-pragmatic characterization of discourse markers. This long-debated question is first addressed by an overview of their classification within linguistic theories, focusing on the delimitation of the class and on the ...
Ricci, Claudia, Rossari, Corinne
core
Special Distribution of Discourse Markers Determined by Genre-Specific Scientific Discourse
Известия Южного федерального университета: Филологические науки, 2017 The article is concerned with the role of discourse markers in denoting the genre of some text or utterance. The analysis is based on proper scientific discourse, including such genres as a monograph, article, lecture and discussion.
Olesya A. Zagorodnova
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Russian Journal of LinguisticsResearchers typically examine metatextual discourse markers as linguistic tools that promote cohesion and logical coherence. Therefore, their functioning beyond these traditional roles remains insufficiently explored.
Olga V. Sokolova
doaj +1 more source