Results 121 to 130 of about 12,381 (255)
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Educação, 2017 As sessões de apresentação de relatos de prática já fazem parte da programação dos Seminários Web Currículo, promovidos pelo Programa de Pós-Graduação em Educação: Currículo da Pontifícia Universidade Católica de São Paulo (PUC-SP). Visando a compreender as contribuições das apresentações de tais práticas, sob a perspectiva dos participantes nas ...
Gonçalves, Lina Maria +2 more
openaire +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Escola Anna Nery, 2009 Objetivou-se discutir o emprego do Grupo Focal (GF) para coleta e do Discurso do Sujeito Coletivo (DSC) para análise de dados em investigações no Campo da Enfermagem. Essas técnicas foram descritas sob o ponto de vista teórico e prático. Exemplificou-se o emprego pelo detalhamento das etapas metodológicas, de uma pesquisa aprovada em comitê de ética ...
Vera Lúcia de Oliveira Gomes +2 more
openaire +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley +1 more source
, 2003 This article makes an the evaluation of the satisfaction, among students of the course: "Training and development of manpower in Health " - CADRHU 2002" , that was offered by the Health State Secretary and Public Health School/USP. In order to do that, the authors used the technical devices of the Discourse of the Collective Subject (Lefèvre e Lefèvre,
Lefevre, Ana Maria Cavalcanti +2 more
openaire +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source