Results 101 to 110 of about 12,381 (255)

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Theoretical-methodological options in qualitative research: social representations and discourse of the collective subject

open access: yes, 2009
The present bibliographical study aimed to introduce Social Representations Theory and the Discourse of the Collective Subject as theoretical-methodological options for the development of research in nursing that is based on common knowledge. Social Representations are popular knowledge, myths, beliefs, customs, which converge on common sense and are ...
Duarte, Sebastião Junior Henrique   +2 more
openaire   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

The application of transpersonal and spiritual care for older adults receiving palliative care

open access: yesRevista Brasileira de Geriatria e Gerontologia
Objective : To identify the perception of nurses regarding spiritual care for older patients undergoing palliative care. Methods : A descriptive study with a qualitative approach was carried out with 27 care nurses at the Hospital Universitário de ...
Johnata da Cruz Matos   +1 more
doaj   +1 more source

Social networks as biased places of memory: the discourse of the collective subject about strike by truck drivers in Brazil

open access: yes, 2020
Se trata de investigación exploratoria cuyo objetivo principal es el de descortinar las relaciones existentes entre memoria colectiva y redes sociales, en especial, el Instagram. Los objetivos específicos son verificar las fotografías relacionadas con la paralización de los camioneros (ocurrida en mayo de 2018) en el Instagram del diario cearense O ...
Sampaio, Denise Braga   +3 more
openaire   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Advantages and disadvantages of livestock farming in Brazil, according to beef chain actors

open access: yesO Mundo da Saúde, 2013
This study aimed at identifying the advantages and disadvantages of beef production for the domestic market and for export according to the perception of the production chain actors in Brazil.
Nelson Roberto Furquim   +1 more
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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