Results 101 to 110 of about 812,156 (301)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

The Open method of co-ordination and the analysis of mutual learning processes of the European employment strategy: methodological and theoretical considerations [PDF]

open access: yes
The purpose of this paper is solely to address two interlinked methodological and theoretical questions concerning the Open Method of Coordination (OMC), using the European Employment Strategy as a case: First, what is the most appropriate approach to ...
Nedergaard, Peter
core   +1 more source

Goodbye Bismarck? : the foreign policy of contemporary Germany [PDF]

open access: yes, 2008
This essay examines the foreign policy discourse in contemporary Germany. In reviewing a growing body of publications by German academics and foreign policy analysts, it identifies five schools of thought based on different worldviews, assumptions about ...
Hellmann, Gunther
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Realization of Communicative Strategies and Tactics through Using the Auto-Ethnonym “Russian

open access: yesНаучный диалог, 2017
The results are presented of the study of the mechanisms of realizing the communicative strategies and tactics in Russian advertising discourse, the language representative of which is auto-ethnonym Russian and corresponding derivatives.
K. A. Sukhareva
doaj   +1 more source

Using miscommunication to discuss communication [PDF]

open access: yes, 2018
The main objective of this study is to delve into a cross-cultural communicative context. There is something uniquely human about the evolution of knowledge though communication.
Griffith, Mary
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

POLITICAL DISCOURSE ANALYSIS OF MEGAWATI'S SPEECH IN THE OPENING OF THE FOURTH CONGRESS OF THE PDIP [PDF]

open access: yes, 2015
The study is about a critical analysis of a political discourse. Using Megawati’s opening speech in the Fourth Congress of the PDIP, I want to find out the ideological model context used by the text producer and the social structure influencing the ...
Nurhayati , Nurhayati
core  

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