Results 51 to 60 of about 57,439 (265)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Stilʹ i diskurs: shodstva i različiâ

open access: yesStylistyka, 2020
The páper provides a critical inlerpretation of too broad, nontermological and trendy use of discourse in the linguistics and stylistics. The author emphasizes that the concept of discourse cannot replace and displace the notion of style because they are
Branko Tošovič
doaj  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Euroscepticism: Levels of Research and Modes of Manifestation

open access: yesAnali Hrvatskog Politološkog Društva, 2006
The aim of the article is to explore some existing defi nitions of Euro-scepticism in empirical research that deal with the problems of joining the European Union by postsocialist countries and with the possibility of their application to the Croatian ...
Nebojša Blanuša
doaj  

Kroppar, dislokationer och politiska praktiker på YouTube

open access: yesKulturella Perspektiv, 2012
This article explores the benefits of political discourse theory in the analysis of self harm video blogs. It is argued that a reworked concept of ‘dislocation’ (e.g.
Anna Johansson
doaj   +1 more source

When ADHD knocks on the door - discourse theory as a frame to explore subject positions and mental wellbeing before diagnosis. [PDF]

open access: yesInt J Qual Stud Health Well-being, 2023
Grønneberg SV   +2 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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