Results 61 to 70 of about 54,162 (265)

Klasskamrater revisited

open access: yesKulturella Perspektiv, 2012
My thesis Classmates was published 1987 and was a late contribution to a theory/political debate that was about to lose its place in the academy. When the Wall fell in 1989, and the neoliberal transformation of Eastern Europe gained momentum, the terms “
Mats Lindqvist
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

On Truth and Emancipation

open access: yesNordicum-Mediterraneum, 2012
This article has two main currents. First, it argues that an affinity or similarity can be identified between the philosophy of Gianni Vattimo (the so-called “Weak Thinking”) and the “Discourse Theory” of Ernesto Laclau and Chantal Mouffe.
Andreas Hjort Bundgaard
doaj  

Det materiella i fokus

open access: yesKulturella Perspektiv, 2012
This article discusses the definition of discourse by Laclau and Mouffe as including also the material, in relation to ethnological applications. It analyses East German material articulations before and after the Fall of the Wall through biographic ...
Sofi Gerber
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Role of Qualitative Interviews in Discourse Theory

open access: yesCritical Approaches to Discourse Analysis across Disciplines, 2012
In discourse theoretical studies the qualitative interview is scarcely treated as a method, but as empirical data. Some important methodological challenges for discourse theory are thereby being obscured.
Jørn Cruickshank
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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