Results 31 to 40 of about 2,220 (219)

The 2013 Election in Zimbabwe: The end of an era [PDF]

open access: yes, 2013
The July 31st 2013 Elections in Zimbabwe ushered in a renewed period of political domination by ZANU(PF) and its President, Robert Mugabe. This election followed five years of a SADC- facilitated Global Political Agreement (GPA), which was put into ...
Raftopoulos, Brian
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The Reconstruction of the Beirut Central District: An urban geography of war and peace

open access: yes, 2015
Three conceptual themes of public-private, temporality, and heritage-modernity are used to develop an urban geography of war and peace of Beirut. During the 1975-1990 Lebanese civil war public space shrank and people retreated deeper into localised ...
Humphreys, David
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

The perception of “insular” England in “insular” Japan

open access: yesЯпонские исследования
The insular position has serious influence on history and mentality. However, this provision “works” only in conjunction with other factors. Japan and England are island nations, but the history of England is characterized by the maximum number of ...
A. N. Meshcheryakov
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Notícies [PDF]

open access: yes, 2014
IV Jornadas Franco-Españolas de Tradición Oral.16th International Society for Folk Narrative Research Congress.IX Trobada del Grup d’Estudis ...
Francés Mira, Anna   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Traditionalism Through the Prism of the Neosentimentalist Discourse (Based on V. Gurkin’s Dramaturgy)

open access: yesJournal of Siberian Federal University. Humanities & Social Sciences, 2016
The article analyzes the specificity of the traditionalism trends functioning in the Russian literature of the second half of the XX century in the context of neosentimentalism discourse. Its universality and functional multiplicity provides its widespread penetration into the literary process of that time and integration with various literary ...
openaire   +3 more sources

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