Results 61 to 70 of about 2,220 (219)
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
The Possibility and Utility of Religious Science in Nasr’s Discourse of Traditionalism
پژوهشنامۀ انتقادی متون و برنامههای علوم انسانی, 2017 The study discuses Professor Seyed Hossein Nasr’s idea of traditionalism; a discourse of traditionalism that seeks to resurrect the divine science relied on divine tradition, perennial philosophy, and intuitive reason. In the negative dimension, acknowledging cognitive, moral, and environmental crises caused by modern sciences and their inefficiency as
openaire +1 more source
The Journal of Political Theory, Political Philosophy and Sociology of Politics Politeia, 2017 The article examines articulation of traditional political values in the actual public discourse of the Russian Orthodox Church (ROC). The study is empirically based on the official documents of the ROC that reflect its position on socio-political issues, statements made by various synodal departments and church hierarchs, as well as statements by the ...
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FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Bullying Perpetration and Homophobic Teasing: Mediation through Gender Role Attitudes. [PDF]
Children (Basel), 2022 Gao Y, Zhang Z, Chen B, Wang X.
europepmc +1 more source
Diversification: towards a new paradigm for Africa’s development [PDF]
This paper is articulated around the following chapters. After this introduction, the first chapter will underscore Africa’s development stakes. This analysis will enable us to tackle the problem of modernizing and diversifying the productive fabric of ...
Ben Hammouda, Hakim +3 more
core +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
A cross-level study of the relationship between ethical leadership and employee constructive deviance: Effects of moral self-efficacy and psychological safety climate. [PDF]
Front Psychol, 2022 Shang L, Yang L.
europepmc +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source