Results 111 to 120 of about 52,498 (263)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
MILITARY-POLITICAL DISCOURSE AS A DISTINCTIVE TYPE OF DISCOURSE
Bulletin of the South Ural State University series Linguistics, 2017 Tamara Khomutova, Ksenia Naumova
openaire +2 more sources
ENGLISH POLITICAL DISCOURSE AS A TYPE OF DISCOURSE: A PHILOLOGICAL ANALYSIS
The article is devoted to the study of the philological phenomena of discourse, political discourse and English-language political discourse. For the first time, the author offers the term of English-language political discourse. Based on the methodology of meta-anthropology, English-language political discourse is the boundary dimension of existence ...
openaire +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Impact of ageing on discourse types: a comparative study. [PDF]
CodasPuttanna D +4 more
europepmc +1 more source
Text and Discourse: Types and Characteristics. The Concept of Discourse in Pragmalinguistics
The term “discourse” nowadays represents one of the central issues in linguistics. Some even equate it with the concept of “text.” This article explores text and discourse, their similarities and differences, and the scope of their application in pragmalinguistics.
openaire +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Embodied meaning in therapeutic discourse during cognitive-behavioral therapy for generalized anxiety disorder: an image schema analysis. [PDF]
Health Psychol Behav MedMohamadpour F, Askarian M.
europepmc +1 more source